摘要
骨质疏松症的发生受到遗传因素的影响,随着分子生物学的发展和疾病遗传学的深入研究,对基因多态性的挖掘无疑是未来骨质疏松症研究的趋势。本文对骨质疏松症及中医证型与相关基因多态性的研究进展作一总结,分析探讨其研究方法及思路,为今后的骨质疏松症防治提供更多的理论依据。
The occurrence of osteoporosis is affected by genetic factors. With the development of molecular biology and the in-depth study of disease genetics, mining of gene polymorphism is undoubtedly the trend of osteoporosis research in the future. This paper will summarize the research progress of osteoporosis, TCM syndrome differentiation and related gene polymorphisms to explore its research methods and ideas, providing more theoretical basis for the prevention and treatment of osteoporosis in the future.
作者
汪洋
杨鸫祥
王洪旭
那俊夫
WANG Yang;YANG Dong-xiang;WANG Hong-xu;NA Jun-fu(Liaoning University of Traditional Chinese Medicine,Shenyang,Liaoning 110847,China;不详)
出处
《中国临床研究》
CAS
2022年第6期866-869,共4页
Chinese Journal of Clinical Research
基金
辽宁省科学技术计划项目(2020JH2/10300068)
中医脏象理论及应用国家教育部重点实验室开放基金(ZYZX1806)。
关键词
骨质疏松症
中医证型
基因多态性
维生素D受体
雌激素受体
Ⅰ型胶原
辨证
Osteoporosis
Traditional Chinese medicine syndrome differentiation
Gene polymorphism
Vitamin D receptor
TypeⅠcollagen
Dialectical