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左室功能异常二尖瓣反流病人MRI影像学参数与肌脂蛋白的相关性分析 被引量:1

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摘要 目的分析左室功能异常二尖瓣反流病人MRI影像学参数与肌脂蛋白(SLN)的相关性。方法选取2016年1月—2019年2月秦皇岛市第三医院诊治的50例二尖瓣反流病人为研究组,另选取13名健康人为对照组,对50例二尖瓣反流病人进行MRI影像检查,测量左室功能及容积,并进行连续心室短轴总和测量,对照组相关数据由第三方实验中心提供。采用免疫印迹法及免疫荧光染色检测SLN蛋白表达。结果研究组左室舒张末期内径和左室收缩期末期内径大于对照组(P<0.05),研究组左室质量指数高于对照组(P<0.05)。二尖瓣反流病人心脏显示左室扩张和心室壁变薄。研究组SLN蛋白染色信号强度高于对照组,且与影像学参数存在相关性。结论SLN作为心房调节因子在左室功能异常二尖瓣反流病人中显著上调,且与影像学参数具有相关性。
出处 《中西医结合心脑血管病杂志》 2022年第12期2253-2256,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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  • 1Beaudoin J, Handschumacher MD, Zeng X, et al. Handschumacher,et al. Mitral valve enlargement in chronic aortic regurgitation as a compen- satory mechanism to prevent functional mitral regurgitation in the dilated left ventricle[ J]. J Am Coil Cardiol, 2013,61 (17) : 1809 - 1816.
  • 2Tibayan FA, Rodriguez F, Zasio MK, et al. Geometric distortions of the mitral valvular - ventricular complex in chronic ischemic mitral regurgi- tation[J]. Circultaion, 2003,108 Suppl 1 :Iil16 - 121.
  • 3Timek TA, Green GR, Tibayan FA, et al. Aorto - mitral annular dy- namics [ J ]. Ann Thorac Surg, 2003,76 ( 6 ) : 1944 - 1950.
  • 4Hueb AC, Jatene FB, Moreira LF, et al. Ventriclar remodeling and mi- tral valve modifications in dilated eardiomyopathy: new insights from an- atomic study [ J ]. J Thorac Cardiovasc Surg, 2002,124 ( 6 ) : 1216 - 1224.
  • 5Chaput M, Handschumacher MD, Tournoux F, et al. Mitral leaflet ad- aptation to remodeling: oceurrenced and adequacy in patients with func- tional mitral regurgitation[J]. Circulation, 2008,118(80) :845 -845.
  • 6Dal - Bianco JP, Aikawa E, Bischoff J, et al. Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for func- tional mitral regurgitation [ J ]. Circulation, 2009,120 ( 4 ) : 334 - 342.
  • 7Otsuji Y, Levine RA, Takeuchi M, et al. Mechanism of ischemic mitral regurgitation [ J ]. J Cardioi, 2008,51 (3) : 145 - 156.
  • 8Di Mauro M, Gallina S, DAmico MA, et al. Functional mitral regurgi- tation : from normal to pathological anatomy of mitral valve[ J]. J Cardi- ol, 2013,163(3) :242 -248.
  • 9Otsuji Y, Haudschumacher MD, Liel- Cohen N, et al. Mechanism of ischemic mitral regurgitation with segmental left ventricular dysfunction: three - dimensional echocardiographic studies in models of acute and chronic progressive regurgitation[J]. J Am Coil Cardiol, 2001,37(2) : 641 - 648.
  • 10Yiu SF, Enriquez - Sarano M, Tribouilloy C, et al. Determinants of the degree of functional mitral regurgitation in patients with systolic left ven- tricular dysfunction: a quantitative clinical study [ J ]. Circulation, 2000,102(12) :1400 - 1406.

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