肠道微生态与创伤的研究进展

Research progress of intestinal microecology and trauma

目的总结肠道微生态与创伤的研究现状和进展,以期为高质有效的创伤救治提供思路。方法对近年来国内外研究肠道微生态与创伤的文献进行分析并综述。结果创伤后肠道微生态发生变化,但创伤对肠道微生态的影响机制目前还不明确,肠道微生态制剂(如益生菌)、粪菌移植、中医治疗等可以维护创伤后肠道微生态。结论创伤与肠道微生物态的关系可能为创伤后改善结局提供有价值的诊断、预防和治疗思路,但创伤对肠道微生态的影响、机制以及干预措施仍需要进一步研究。

Objective To summarize the research status and progress of intestinal microecology and trauma,in order to provide ideas for high-quality and effective treatment of trauma.Method The literatures on intestinal microecology and trauma at home and abroad in recent years were analyzed and reviewed.Results Intestinal microecology changed after trauma,but the mechanism of trauma on intestinal microecology was not clear.Intestinal microecological agents(such as probiotics),fecal bacteria transplantation,and traditional Chinese medicine treatment could maintain post-traumatic intestinal microecology.Conclusions The relationship between trauma and intestinal microbiota may provide valuable diagnostic,preventive,and therapeutic insights for improving the outcome after trauma,but the impact,mechanism,and intervention measures of trauma on intestinal microecology still need to be further studied.