认知训练在遗忘型轻度认知功能障碍患者中应用的研究进展

Research progress of cognitive training in patients with amnestic mild cognitive impairment

阿尔茨海默病(AD)是常见的进行性中枢神经系统退行性疾病,以进行性认知功能下降为主要临床特征,是导致痴呆的主要原因。遗忘型轻度认知功能障碍(a-MCI)是轻度认知功能障碍(MCI)的一种亚型。研究表明,a-MCI大多会进展为AD,积极干预a-MCI是延缓或减少AD发生的关键。目前用于治疗a-MCI的药物均缺少大样本的循证医学证据,临床科研工作者越来越关注认知训练在a-MCI非药物治疗领域的研究。认知训练的研究在a-MCI患者的非药物干预方面具有广阔的应用前景。现就认知训练在a-MCI患者临床中应用的研究进展进行综述。

Alzheimer disease(AD)is a common progressive degenerative disease of central nervous system,with progressive cognitive decline as the main clinical feature,and is the main cause of dementia.Amnestic mild cognitive impairment(a-MCI)is a subtype of mild cognitive impairment(MCI).Studies have shown that most of a-MCI will progress to AD,and active intervention of a-MCI is the key to delay or reduce the occurrence of AD.Currently,the drugs used for the treatment of amnestic MCI(a-MCI)lack large sample evidence-based medical evidence,and clinical researchers are paying more and more attention to the research of cognitive training in the field of non-drug treatment of a-MCI.The research of cognitive training has broad application prospect in the non-drug intervention of patients with a-MCI.This paper reviews the research progress of cognitive training in the clinical application of patients with a-MCI.