快速现场评价技术在肺癌诊断中的应用价值

Application value of rapid on-site evaluation technology in diagnosis of lung cancer

目的探讨快速现场评价(rapid on-site evaluation,ROSE)技术在肺癌诊断中的临床价值。方法收集疑似肺癌病例45例,活检标本后同时行ROSE技术及病理检查,以病理学检查为金标准,计算ROSE检查的符合率。记录两者出具报告所需的时间。结果45例患者中,经支气管镜检查的病例有29例,CT引导下经皮肺穿刺检查12例,胸膜活检术及胸腔闭式引流术4例。病理标本中均可诊断肺癌,ROSE标本44例可诊断肺癌,1例患者不能明确诊断,ROSE技术的符合率达97.78%。ROSE报告取得标本后的4~52 min内出具,平均时间(13.58±8.67)min;病理报告在2832~15885 min获得,平均时间(6908.76±5260.39)min,两种诊断比较,差异有统计学意义(t=8.79,P=0.001)。结论ROSE技术与病理学检查诊断符合率高,ROSE技术较病理学检查具有诊断快速的优势。

Objective To explore the clinical significance of rapid on-site evaluation(ROSE)in the diagnosis of lung cancer.Methods A total of 45 cases of suspected lung cancer were collected,and ROSE technique and pathological examination were performed simultaneously after biopsy.The coincidence rate of ROSE examination was calculated by taking pathological examination as the gold standard.The time required for both to produce a report was recorded.Results Of the 45 biopsy specimens,there were 29 cases obtained with bronchoscopy,12 cases obtained with CT-guided percutaneous lung puncture,and 4 cases obtained with pleural biopsy and closed thoracic drainage.All of lung cancer could be diagnosed in pathological specimens,44 cases could be diagnosed in ROSE specimens,1 case could not be clearly diagnosed.The coincidence rate of ROSE technique was 97.78%.The ROSE report was issued within 4~52 min after obtaining the specimen,with an average time of(13.58±8.67)min;the pathological report was obtained within 2832~15885 min,with an average time of(6908.76±5260.39)min.The difference between the two diagnoses was statistically significant(t=8.79,P=0.001).Conclusion ROSE technology has a high coincidence rate with pathological examination,and ROSE technology has the advantage of rapid diagnosis compared with pathological examination.