通淋排石汤辅助治疗经皮肾镜碎石术后结石残留的疗效观察

Effect of Tonglin Paishi Decoction in the Adjuvant Treatment of Kidney Stones after Percutaneous Nephrolithotomy

目的:探讨肾结石患者经皮肾镜碎石手术后应用通淋排石汤辅助治疗的临床效果。方法:选取2019年1月至2021年1月在新郑市中医院确诊的76例气滞血瘀型肾结石患者,采用随机分组将患者分为观察组和对照组,各38例。对照组采用经皮肾镜碎石术治疗,观察组在对照组的治疗基础上用通淋排石汤辅助治疗,持续治疗14 d。比较两组治疗前后尿痛、小便不畅和小腹绞痛症候评分变化和治疗后临床疗效评定,检测患者肾功能指标,记录治疗期间的不良反应发生情况。结果:观察组患者治疗总有效率为92.11%,高于对照组的78.95%,差异具有统计学意义(P<0.05);治疗后两组患者尿痛、小便不畅和小腹绞痛评分低于治疗前,且观察组患者治疗后评分低于对照组,差异具有统计学意义(P<0.05);治疗后两组患者的血肌酐(SCr)和尿素氮(BUN)比较,差异无统计学意义(P>0.05);观察组患者的不良反应总发生率为5.26%,低于对照组的7.86%,差异无统计学意义(P>0.05)。结论:通淋排石汤辅助治疗可以明显提高经皮肾镜碎石术术后结石残留的临床症状,提高排石率。

Objective To investigate the clinical effect of Tonglin Paishi decoction in the treatment of patients with kidney stones after percutaneous nephrolithotomy.Methods A total of 76 patients with kidney stones of Qi stagnation and blood stasis type diagnosed in Xinzheng Hospital of Traditional Chinese Medicine from January 2019 to January 2021 were selected and randomly divided into an observation group and a control group,with 38 cases in each group.The control group was treated with percutaneous nephrolithotomy,and the observation group was treated with Tonglin Paishi decoction on the basis of the treatment of the control group for 14 days.The changes of urinalgia,dyspuria and colic syndrome scores before and after treatment and clinical efficacy evaluation after treatment were compared between the two groups.Renal function indexes of patients were detected,and the occurrence of adverse reactions during treatment were recorded.Results The total effective rate of the observation group was 92.11%,which was higher than 78.95%of the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of dysuria,dyspuria and colic in the two groups were lower than those of before treatments,and the scores of the observation group were lower than those of the control group,the differences were statistically significant(P<0.05).After treatment,there was no significant difference in serum creatinine(SCr)and urea nitrogen(BUN)between the two groups(P>0.05).The total incidence of adverse reactions in the observation group was 5.26%,which was lower than 7.86%in the control group,and the difference was not statistically significant(P>0.05).Conclusion The adjuvant treatment of Tonglin Paishi decoction can significantly improve the clinical symptoms of residual stones and stone removal rate after percutaneous nephrolithotripsis.