德尔塔毒株新冠病毒肺炎患者临床分型影响因素分析

Analysis of Influencing Factors on Clinical Classification of Patients with COVID-19 Delta Variant in Dehong Prefecture of Yunnan Province

目的:探讨Delta毒株新冠病毒肺炎(COVID-19)患者不同临床分型的影响因素,为更好地防控疫情传播和病情恶化提供理论依据。方法:基于2021年9—12月期间确诊的云南省德宏州本土感染Delta毒株COVID-19患者141例,应用单因素和多因素logistics回归模型分析轻型/普通型感染的影响因素。结果:本研究共纳入141例本土Delta毒株COVID-19患者,男性45例(31.91%),女性96例(68.09%)。多因素logistic回归分析显示,调整潜在的混杂因素后,年龄≥30岁的人群感染Delta毒株COVID-19出现轻型/普通型临床症状的危险性增加(OR=2.30,95%CI:1.14~4.67),且年龄每增加1岁,出现轻型/普通型临床症状的危险性就增加2%(OR=1.02,95%CI:1.00~1.04)。这一现象在女性人群中更加显著,而在男性人群中差异无统计学意义。结论:年龄较大的Delta毒株COVID-19女性患者发生轻型/普通型临床症状的危险性增加。

OBJECTIVETo explore the influencing factors of different clinical types of patients diagnosed as Delta strain of Coronavirus Disease 2019( COVID-19), and to provide theoretical basis for better prevention and control of the spread of epidemic and the deterioration of the COVID-19. METHODS Based on the confirmed patients with COVID-19 living in Dehong Prefecture of Yunnan province from September to December 2021, univariate and multivariate logistic regression models were used to analyze the influencing factors of mild/common infection. RESULTS A total of 141 patients with COVID-19( Delta Variant) were included in the study, including 45 males( 31.91%) and 96 females( 68.09%). Multivariate logistic regression analysis showed that after adjusting for potential confounding factors, patients with COVID-19( Delta Variant) aged ≥30 years had an increased risk of developing mild/common clinical symptoms( OR=2.30, 95%CI: 1.14~4.67), and for every 1-year increase in age, the risk of developing mild/common clinical symptoms increased by 2%( OR=1.02, 95%CI: 1.00~1.04). The phenomenon was more pronounced in the female population, but not statistically significant in the male population. CONCLUSION Older females with COVID-19( Delta strain) have an increased risk of developing mild/common clinical symptoms.