正念减压疗法对精神分裂症后抑郁的临床疗效观察

Observation on the Clinical Effect of Mindfulness Decompression Therapy on Depression after Schizophrenia

目的探讨正念减压疗法对精神分裂症后抑郁的临床疗效。方法选取2017年1月—2019年1月于该院住院的80例精神分裂症后抑郁患者,以随机法分为对照组和观察组,各40例。对照组患者接受新型抗精神病药物联合选择性5-羟色胺再摄取抑制剂类抗抑郁药治疗,观察组在此基础上加用正念减压疗法。对比分析两组患者干预前、干预6个月后的抑郁、焦虑情绪和自尊程度。结果干预后,两组汉密尔顿抑郁量表(HAMD)评分均低于干预前,且观察组评分低于对照组,组间差异有统计学意义(P<0.05)。干预后,两组焦虑自评量表(SAS)评分均低于干预前,且观察组评分低于对照组,组间差异有统计学意义(P<0.05)。干预后,两组自尊量表(SES)评分均高于干预前,且观察组评分高于对照组,组间差异有统计学意义(P<0.05)。结论正念减压疗法治疗精神分裂症后抑郁,不仅能改善患者的抑郁焦虑情绪,提高治疗依从性,还可提高患者的个人自尊心和自我价值。

Objective To explore the clinical effect of mindfulness decompression therapy on depression after schizophrenia.Methods 80 patients with post-schizophrenia depression who were hospitalized in the hospital from January 2017 to January 2019 were selected and randomly divided into a control group and an observation group,with 40 cases in each group.Patients in the control group were treated with new antipsychotics combined with selective serotonin reuptake inhibitor antidepressants,and the observation group was treated with mindfulness decompression therapy on this basis.The depression,anxiety and self-esteem of the two groups of patients before intervention and 6 months after intervention were compared and analyzed.Results After the intervention,the Hamilton depression rating scale(HAMD)scores of the two groups were lower than those before the intervention,and the score of the observation group was significantly lower than that of the control group,and that of the difference between the groups was statistically significant(P<0.05).After the intervention,the two groups'anxiety self-rating scale(SAS)scores were lower than before the intervention,and the score of the observation group was significantly lower than the control group,and the difference between the groups was statistically significant(P<0.05).After the intervention,the self-esteem scale(SES)scores of the two groups were higher than those before the intervention,and the score of the observation group was significantly higher than that of the control group,and the difference between the groups was statistically significant(P<0.05).Conclusion Mindfulness decompression therapy for post-schizophrenia depression can not only improve the patient's depression and anxiety,improve treatment compliance,but also improve the patient's personal self-esteem and self-worth.