江苏省2664例性病和妇科门诊女性患者淋球菌感染状况及影响因素分析

High Prevalence of Neisseria Gonorrhoeae Infection in Women Attending STD and Gynecology Clinics in Jiangsu Province

目的 了解江苏省性病和妇科门诊女性患者淋球菌(Neisseria gonorrhoeae,NG)感染状况及其可能的影响因素。方法 2018-2019年在全省性病哨点医院的性病和妇科门诊招募求诊者作为调查对象,进行问卷调查及实验室NG核酸检测,计算NG感染率;采用Logistic回归模型分析NG感染可能的影响因素。结果 共招募女性就诊者2 664名,NG感染206例,感染率为7.73%(95%CI:6.68~8.79)。进行社会人口学和行为学特征分析,发现来自性病门诊的患者NG感染率(10.19%)较妇科门诊高;患者地域为苏南(8.91%)和苏北(8.28%)的NG感染率较高;相对于江苏省户籍,户籍为其他省(11.41%)的患者NG感染率较高;从事服务业人员(12.01%) NG感染率较高。多因素分析结果显示,服务业从业人员、来自苏南和苏北,性行为频率2次/周或更多的患者更容易感染NG(P<0.05)。结论 江苏省性病和妇科门诊女性患者淋球菌感染率较高,应加强对性病门诊就诊者、流动人口等重点人群的淋病检测、干预及治疗。

Objective To understand the prevalence of Neisseria gonorrhoeae(NG) infection and its associated factors in women attending STD and gynecology clinics in Jiangsu Province.Methods In this cross-sectional survey, women attending STD and gynecology clinics in the province from 2018 to 2019 were recruited.Cervical swab specimens were collected to test for NG with the NAAT method and calculate the prevalence.A logistic regression model was used to identify factors associated with NG infection.Results A total of 2 664 female outpatients were recruited.The prevalence of NG infection was 7.73%(95%CI:6.68%~8.79%).Among those, the higher NG prevalence was observed in participants from STD clinics(10.19%),South Jiangsu(8.91%) and North Jiangsu(8.28%),with registered residence in other provinces(11.41%),and with the occupation of service personnel(12.01%).Female outpatients who worked as service personnel, lived in South Jiangsu or North Jiangsu, and had sexual intercourse twice or more per week were more likely to contract NG(all P<0.05).Conclusion Our study showed a high prevalence of NG infection in women attending STD and gynecology clinics in Jiangsu province.Gonorrhea screening, intervention and treatment should be enhanced to reduce transmission in certain groups such as STD outpatients and migrant populations.