丙泊酚联合瑞芬太尼对脑出血患者术后自主呼吸恢复时间的影响

Effect of Propofol Combined with Remifentanil on Recovery Time of Spontaneous Respiration in Patients with Cerebral Hemorrhage after Operation

目的:探讨丙泊酚联合用药对脑出血患者术后自主呼吸恢复时间的影响。方法:选取2019年1月至2020年10月佳木斯市中心医院收治的脑出血手术患者90例为研究对象,根据不同的治疗方案平均分为对照组和观察组,每组45例。对照组采用丙泊酚联合芬太尼进行麻醉,观察组采用丙泊酚联合瑞芬太尼进行麻醉,评价两组患者丙泊酚用量、自主呼吸恢复时间、苏醒时间,比较两组患者不良反应发生情况。结果:手术期间,观察组患者的丙泊酚用量少于对照组,手术后,患者自主呼吸恢复时间、苏醒时间短于对照组,差异具有统计学意义(P<0.05)。手术期间及手术后,观察组患者的不良反应总发生率低于对照组,差异具有统计学意义(P<0.05)。结论:丙泊酚联合瑞芬太尼对脑出血患者术后自主呼吸恢复时间明显优于芬太尼联合丙泊酚,起效作用迅速,临床使用不良反应少。

Objective To investigate the effect of propofol combined with the remifentanil on recovery time of spontaneous breathing in patients with cerebral hemorrhage after operation.Methods A total of 90 cerebral hemorrhage patients admitted to Jiamusi Central Hospital from January 2019 to October 2020 were selected as the research objects,and divided into a control group and an observation group according to different treatment regimens,with 45 patients in each group.The control group was anesthetized with propofol combined with fentanyl,and the observation group was anesthetized with propofol combined with remifentanil.The dosage of propofol,recovery time of spontaneous breathing and recovery time of patients in the two groups were evaluated,and the occurrence of adverse reactions in the two groups were compared.Results During the operation,the dosage of propofol in the observation group was less than that in the control group,and the recovery time of spontaneous breathing and recovery time of patients after the operation were shorter than those in the control group,with statistically significant differences(P<0.05).During and after surgery,the total incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Propofol combined with remifentanil has significantly better recovery time of spontaneous breathing in patients with intracerebral hemorrhage than fentanyl combined with propofol,with rapid effect and fewer clinical adverse reactions.