摘要
Dear Editor,Temperate bacteriophages are widely distributed in bacteria isolated from different natural environments(Howard-Varona et al.,2017).The phages normally lead to lysogenic infection and merge their genetic components into the bacterial chromosome.Among the temperate phages,linear plasmid phages are atypical because of their capability to reside in host cells as linear ds DNA with covalently closed ends,rather than being integrated in host genomes in the form of prophages(Ravin et al.,2000;Ravin,2011).
基金
financially supported by the National Natural Science Foundation of China(Grant No.91851113,41921006)
the National Key R&D Program of China(Grant No.2018YFC0309800)。
