摘要
Dear Editor,Enterovirus 71(EV71)belongs to the genus Enterovirus,family Picornaviridae(Oberste et al.,1999).It was first isolated from patients with central nervous system diseases in California between 1969 and1974(Schmidt et al.,1974)and has spread worldwide(Solomon et al.,2010).EV71 infection usually causes mild,self-limiting hand,foot,and mouth disease in children.Acute EV71 infection may also cause severe polio-like neurological diseases and significant mortality.
基金
supported by the National Natural Science Foundation of China grants(No.31870827 to X Zhao,No.31970169 to X Zhou)
the National Key Research and Development Program of China grant(No.2019YFA0802701 to X Zhao)
the Zhejiang Sci-Tech University Research Startup grants(No.19042401-Y to M Miao)
the Zhejiang Sci-Tech University Youth Innovation grants(No.20042140-Y to M Miao)。
