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Matrisomal genes in squamous cell carcinoma of head and neck influence tumor cell motility and response to cetuximab treatment

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摘要 Dear Editor,Head and neck squamous cell carcinoma(HNSCC)is the sixth most common cancer globally[1,2].Despite the improvement in treatment modalities,up to 50%of HNSCC patients still develop recurrent/metastatic(R/M)disease[3],and platinum-based chemotherapy with cetuximab and/or pembrolizumab has become the standard of care[4].However,R/M HNSCC is challenging to treat,the prognosis is poor,and there is an unmet need for new therapeutic targets.
出处 《Cancer Communications》 SCIE 2022年第4期355-359,共5页 癌症通讯(英文)
基金 This work was supported by funding from the National Medical Research Council NMRC/CSA-INV/0025/2017,MOH-000375-01 and NCCRF-YR2018-JAN-SUG2 Su Bin Lim is supported by the National Research Foundation of Korea(2021R1F1A1064122,2020R1A6A1A03043539,and 2020M3A9D8037604)and the new faculty research fund of Ajou University School of Medicine.
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