胃癌化疗患者并发导管相关性感染的危险因素分析及其防治对策

Analysis of Risk Factors of Catheter-associated Infection in Patients Undergoing Chemotherapy for Gastric Cancer and Their Prevention and Treatment Measures

目的:探究胃癌化疗患者外周静脉穿刺引发的导管相关性感染的危险因素,并提出相应防治对策。方法:选取2019年11月—2020年12月河南科技大学第一附属医院收治的行外周静脉穿刺的130例胃癌化疗患者作为研究对象,根据是否发生导管相关性感染将其分为感染组(n=28)和非感染组(n=102),采用回归分析法分析外周静脉穿刺引起患者发生导管相关性感染的危险因素。结果:单因素分析结果显示,年龄、体质量指数、导管移动、导管留置时间、合并糖尿病与导管相关性感染的发生存在相关性(P<0.05);多因素Logistic回归分析结果显示,年龄>75岁、体质量指数>24、有导管移动、导管置留时间>60 d、有合并糖尿病是导管相关性感染发生的独立危险因素。结论:年龄、体质量指数、导管移动、导管留置时间、合并糖尿病与导管相关性感染的发生密切相关,临床在治疗和护理时应充分考虑,并采取积极措施,防止或减少感染的发生。

Objective:To explore risk factors of catheter-associated infection caused by peripheral venipuncture in patients undergoing chemotherapy for gastric cancer,and propose corresponding prevention and treatment measures.Methods:130 patients undergoing chemotherapy for gastric cancer who were admitted to the First Affiliated Hospital of Henan University of Science and Technology for peripheral venipuncture from November 2019 to December 2020 were selected as research subjects,and they were divided into infected(n=28)and non-infected(n=102)groups according to occurrence of catheter-associated infection,to analyze risk factors of catheter-associated infections caused by peripheral venipuncture by regression analysis method.Results:Univariate analysis results showed that age,body mass index,catheter mobility,catheter retention time,and combined diabetes were associated with catheter-associated infection(P<0.05);multivariate logistic regression analysis results showed that age>75 years old,body mass index>24,catheter mobility,catheter retention time>60 d,and combined diabetes were independent risk factors for catheter-associated infection.Conclusion:Age,body mass index,catheter mobility,catheter retention time,and combined diabetes are closely related to the occurrence of catheter-associated infection and should be fully considered in clinical treatment and care,and active measures should be taken to prevent or reduce infection.