某地区呼吸道病原体流行病学调查

Epidemiological investigation of respiratory pathogens in an area

目的 通过对2019年在该院就诊的呼吸道感染患者进行呼吸道病原体抗原7项检测,分析呼吸道病原体的流行病学特征,为疾病的预防和监控提供依据。方法 提取患者鼻咽拭子,采用直接免疫荧光法检测7种呼吸道病原体抗原,包括副流感病毒1型(PIV1)、副流感病毒2型(PIV2)、副流感病毒3型(PIV3)、甲型流感病毒(FluA)、乙型流感病毒(FluB)、呼吸道合胞病毒(RSV)、腺病毒(ADV)。结果 12196例患者中,检出呼吸道病毒669例,检出率为5.47%。其中检出率最高的是甲型流感病毒(1.92%)和呼吸道合胞病毒(1.80%),其次分别为PIV3、FluB、ADV、PIV1、PIV2。男性与女性检出率分别为5.64%、5.31%,差异无统计学意义。各年龄段患者呼吸道病原体感染率不同,婴儿组感染率最高为21.71%,幼儿组次之为13.78%,两者明显高于学龄前组、学龄组与成人组。所有年龄段不同月份各病原体检出率不同,FluA与RSV检出率最高,其主要分布于11月、12月、1月、2月,PIV3主要高发于4月、5月、6月、7月、8月,FluB高发于3月、4月,其余散在分布。结论 该地区呼吸道感染患者呼吸道病原体主要是FluA与RSV,男女感染率无显著差异,婴幼儿发病率较高,成人发病率偏低,秋冬季相对高发。

Objective To analyze 7 tests of respiratory pathogen infection in respiratory pathogen infection in the First Affiliated Hospital of Chengdu Medical College,analyze the epidemiological characteristics of respiratory pathogens,and provide a basis for the prevention and monitoring of the disease.Methods The patient′s nasopharyngeal swab is extracted,and seven respiratory pathogens antigen is detected by direct immunofluorescence,including a sub-fluvophilic virus type 1(PIV1),sub-fluvophilic virus type 2(PIV2),sub-fluvophilic 3 type(PIV3),A-type Influenza virus(Flua),fluorinated virus(FLUB),respiratory syncytial virus(RSV),adenovirus(ADV).Results Twelve thousand one hundred and ninety-six patients,669 cases of respiratory tract viruse were detected,and the detection rate was 5.47%.Among them,the highest detection rate is an influenza virus(1.92%)and respiratory syncytial virus(1.8%),followed by sub-fluvophilic virus 3 type,hem influenza virus,adenovirus,sub-fluvophilic virus 1 type,pair flu Virus 2 type.Male and female detection rates were 5.64%,5.31%,respectively,no significant differences.The respiratory pathogen infection rate in each age is different,and the infant group infection rate is 21.71%,and the child group is 13.78%,both significantly above the preschool group,the school age group and the adult group.All patient detection rates of all pathogens and respiratory syncyties in different months were the highest,mainly from November,December,January,February,January,February,and the deputy flu virus 3 mainly April,May,June,July,August,the fluvosis in March,in April,and the rest were scattered.Conclusion The respiratory pathogens in respiratory infections in the region is mainly a virus and respiratory syncytial virus.There is no significant difference in the infection rate of men and women.The incidence of infants and young children is high.The incident is low,and autumn is relatively high.