司库奇尤单抗成功治疗3例传统疗效不佳的红皮病型银屑病

Successful treatment of three cases of erythrodermic psoriasis with secukinumab

目的 探析对收治传统治疗疗效不佳红皮病型银屑病患者应用司库奇尤单抗治疗的临床效果。方法 纳入2017年2月~2021年12月间接受治疗的红皮病型银屑病患者3例为分析对象,均接受传统方案治疗后病情控制效果不佳。对患者应用司库奇尤单抗治疗方案干预,对患者资料进行整理并分析治疗前后病情评价差异。结果 治疗前后PASI评分(Psoriasis area and severity index)、DLQI评分(Dermatology quality of life index)和IGA评分(Investigator’s global assessment,IGA)均达到临床预期效果。结论 司库奇尤单抗治疗红皮病型银屑病起效迅速,疗效显著,安全性高,无明显不良反应。

Objective To explore the clinical effect of secukinumab in the treatment of patients with erythrodermic psoriasis with poor response to traditional therapy.Methods Three patients with erythrodermic psoriasis who received treatment from February 2017 to December 2021 were included as the analysis objects,all of whom received traditional treatment with poor disease control effect.The patients were intervened with secukinumab treatment plan,and the patient data were sorted out and the differences in condition evaluation before and after treatment were analyzed.Results The PASI(Psoriasis area and severity index),DLQI(Dermatology quality of life index) and IGA(Investigator’s global assessment,IGA) scores before and after treatment all achieved the expected clinical results.Conclusion Secukinumab in the treatment of erythrodermic psoriasis has a rapid onset,significant curative effect,high safety,and no obvious adverse reactions.