老年胃息肉合并结直肠息肉发病的危险因素分析

Analysis on risk factors for the development of gastric polyps complicated with colorectal polyps in the elderly

目的探究老年胃息肉合并结直肠息肉发病的危险因素。方法分析2019年8月至2021年5月蚌埠医学院第二附属医院消化内科收治的行内镜下黏膜切除术的80例老年患者的临床资料,根据肠镜检查结果,分为对照组和观察组,每组各40例,对照组为单纯性胃息肉患者,观察组为胃息肉合并结直肠息肉患者,记录两组患者的临床资料、病史、息肉特征。结果对照组和观察组患者中吸烟、饮酒、胃息肉>5 mm、高血压因素比较,差异均无统计学意义(P>0.05);观察组患者中男性、脂肪肝、胃肠息肉家族史、冠心病的患病风险明显高于对照组,差异有统计学意义(P<0.05);多因素logistic回归分析显示脂肪肝、胃肠息肉家族史、冠心病、男性为老年胃息肉合并结直肠息肉的危险因素。结论对冠心病和脂肪肝以及合并有胃肠息肉家族史的老年男性患者,应当按时进行胃肠镜检查,以便早期采取干预和治疗措施,防止病变。

Objective To investigate the risk factors for the development of gastric polyps complicated with colorectal polyps in the elderly.Methods The clinical data of 80 elderly patients who underwent endoscopic mucosal resection in the Department of Digestive Medicine of the Second Affiliated Hospital of Bengbu Medical College from August 2019 to May 2021 were analyzed.These patients were divided into the control group(patients with simple gastric polyps)and the observation group(patients with gastric polyps complicated with colorectal polyps)based on the results of colonoscopy,with 40 patients in each group.The clinical data,medical history and polyp characteristics of the patients in both groups were recorded in detail.Results There were no statistically significant differences between the control group and the observation group in the factors such as smoking,alcohol consumption,gastric polyps>5 mm,and hypertension(P>0.05).The risk for the development of gastric polyps complicated with colorectal polyps was significantly higher in those patients being male and with fatty liver,family history of gastrointestinal polyps and coronary heart disease in the observation group than those patients in the control group,with statistically significant differences(P<0.05).Multivariate logistic regression analysis showed that fatty liver,family history of gastrointestinal polyps,coronary heart disease,and male were the risk factors of gastric polyps complicated with colorectal polyps in the elderly.Conclusion Elderly male patients with coronary heart disease,fatty liver,and family history of gastrointestinal polyps should undergo gastroscopy on time for early intervention and treatment to prevent lesions.