三七活骨丸联合体外冲击波治疗早期气滞血瘀型股骨头缺血性坏死的临床疗效观察

Clinical Efficacy of Sanqi Huogu Pill Combined with Shock Wave on the Treatment of Early Osteonecrosis of Femoral Head

目的:探讨三七活骨丸联合体外冲击波(Extracorporeal Shock Wave,ESW)治疗早期气滞血瘀型股骨头缺血性坏死的临床疗效。方法:选取2020年1月至2021年7月就诊的早期(ARCO分期为Ⅰ、Ⅱ期)气滞血瘀型股骨头缺血性坏死患者72例,按照随机数字表法随机分为两组(治疗组和对照组各36例)。对照组采用体外冲击波治疗,治疗组在对照组的基础上给予本院自制中成药制剂三七活骨丸。比较两组患者治疗后的临床疗效,包括视觉模拟评分法(Visual Analogue Scale,VAS)评分、Harris评分、血脂指标及血液流变学指标。结果:两组患者接受治疗后,VAS评分、Harris评分、血脂指标及血液流变学指标均有改善,三七活骨丸联合体外冲击波治疗的效果更显著,差异有统计学意义(P<0.05)。结论:三七活骨丸联合体外冲击波治疗早期气滞血瘀型股骨头缺血性坏死疗效确切。

Objective:To explore the clinical efficacy of Sanqi Huogu pill combined with extracorporeal shock wave(ESW)on the treatment of early osteonecrosis of femoral head(ONFH)with Qi stagnation and blood stasis.Methods:72 patients with early stage(ARCO stageⅠand stageⅡ)osteonecrosis of the femoral head treated from January 2020 to July 2021 were divided into two groups.The control group was treated with shock wave in vitro.Based on the control group treatment,the treatment group was given the Sanqi Huogu pill that is a home-made Chinese patent medicine preparation made by hospital.The differences in the clinical efficacy(including visual analogue scale(VAS)scores,Harris scores,blood lipid index and blood rheological index)before and after treatment were compared.Results:After receiving the treatment,VAS scores,Harris scores,blood lipid index and blood rheological index of patients in two groups all improved.The efficacy of giving Sanqi Huogu pill combined with shock wave treatment was more effective,and the difference had statistically significant(P<0.05).Conclusion:The efficacy of Sanqi Huogu pill and extracorporeal shock wave on early osteonecrosis of the femoral head is exact.