针灸推拿联合川桂止痛膏治疗膝关节滑膜炎61例

61 Cases Study on Acupuncture and Massage Combined with Chuangui Zhitong Ointment on the Treatment of Knee Joint Synovitis

目的:观察针灸推拿联合川桂止痛膏治疗肝肾亏虚兼寒湿痹阻型膝关节滑膜炎的临床疗效。方法:选取2020年1月至2021年5月收治的共计61例肝肾亏虚兼寒湿痹阻型膝关节滑膜炎患者。采用针灸推拿联合川桂止痛膏治疗,采用Lysholm评分监测治疗前后膝关节症状体征、膝关节周径、膝关节屈伸度功能评分及关节液中IL-1、IL-6、TNF-α炎症因子水平,根据《中药新药临床研究指导原则》评定临床疗效,进行统计分析。结果:61例患者治疗4周后运动功能评分、膝周径、膝屈伸度及炎症因子指标值较治疗前均下降,差异有统计学意义(P<0.05)。结论:针灸推拿联合川桂止痛膏在改善肝肾亏虚兼寒湿痹阻型膝关节滑膜炎造成的肿胀、缓解疼痛、恢复关节功能等方面具有较好疗效,能降低关节液中炎症因子的表达,且安全有效。

Objective:To observe the clinical efficacy of acupuncture and massage combined with Chuangui Zhitong ointment on the treatment of liver-kidney deficiency combined with cold-dampness obstruction type knee joint synovitis.Methods:A total of 61 patients with liver-kidney deficiency combined with cold-dampness obstruction type knee joint synovitis admitted to hospital from January 2020 to May 2021 were selected.Acupuncture and massage combined with Chuangui Zhitong ointment were used for treatment,and Lysholm score was used to monitor the symptoms and signs of knee joint,knee joint circumference,knee joint flexion and extension function score before and after treatment.The inflammatory factor expression of IL-1,IL-6 and TNF-αin synovial fluid before and after treatment were detected.The clinical efficacy was evaluated according to the Guidelines for Clinical Research of New Chinese Medicines,and the statistical analysis was conducted.Results:After 4 weeks of treatment,the motor function score,knee circumference,knee flexion and extension and inflammatory factor index values in 61 patients were decreased compared with that before treatment(P<0.05).Conclusion:The acupuncture and massage combined with Chuangui pain relief ointment has comparative advantages in improving the swelling caused by liver-kidney deficiency combined with cold-dampness obstruction type knee joint synovitis,relieving pain and restoring joint function.It can reduce the expression of inflammatory factors in synovial fluid,which is safe and effective.