活血类中成药在心肌梗死后心脏修复中的作用

Effects of Chinese patent medicine for activating blood circulation on cardiac repair after myocardial infarction

心肌梗死是高发病率、高死亡率的一种心血管疾病,严重危害人类健康,梗死后不良的修复方式很大程度影响了人们的生活质量,科学家们一直致力于探索心肌梗死后修复的治疗方式,争取心肌梗死患者最佳的预后。活血类中成药对于心肌梗死的治疗历史悠久,可多靶点、多环节、多途径降低心肌梗死后心肌损伤,促进心脏功能修复,本文主要对几种具有代表性的活血类中成药近几年来在心肌梗死后心脏修复中的药理作用以及临床研究进展进行总结,为中医药治疗急性心肌梗死提供科学依据。

Myocardial infarction(MI) is a cardiovascular disease with high morbidity and mortality,which seriously endangers human health.Poor ways of repair after MI may damage people’s life quality,therefore scientists have been committed to exploring the way of myocardial repair after MI to strive for a better prognosis of these patients.Chinese patent medicines for blood circulation activation have a long history of use in treatment of MI,where they have been shown to attenuate myocardial injury after MI and promote cardiac repair with multiple targets,links and pathways.This review focuses on a few representative Chinese patent medicines for MI and summarizes their pharmacological effects and clinical research in cardiac repair following MI,effectively providing scientific foundation on treating MI with Chinese patent medicines.