蛇足石杉主要活性成分及其生物合成研究进展

Active compounds and their biosynthesis of Huperzia serrata

蛇足石杉Huperzia serrata为我国珍稀濒危药用植物,可供利用的资源极其有限,其所含石杉碱甲对治疗阿尔茨海默病、改善学习记忆等具有显著的疗效。对蛇足石杉的主要活性成分进行系统综述,基于现有研究推导了其活性成分可能的生物合成途径,为其资源开发利用和活性成分的生物合成提供科学参考。

Due to the extremely limited resources available,Huperzia serrata is a rare and endangered medicinal plant in China.Moreover,clinical studies have shown that huperzine A from H.serrata is highly effective in treatment of Alzheimer’s disease and improving learning and memory abilities.Active compounds from H.serrata were reviewed in this paper,and the possible biosynthetic pathway of active compounds of H.serrata were concluded,in order to provide scientific reference for exploitation and utilization of its resources and biosynthesis of its active ingredients.