肉芽肿性小叶性乳腺炎与乳腺浸润性小叶癌超声声像图特征对比研究

Comparison of ultrasonographic features in the granulomatous lobular mastitis and infiltrating lobular carcinoma of the breast

目的:总结并对比肉芽肿性小叶性乳腺炎(granulomatous lobular mastitis,GLM)与乳腺浸润性小叶癌(infiltrating lobular carcinoma of the breast,ILC)的超声声像图特征,以期提高对两者的鉴别诊断。方法:回顾并分析北京协和医院28个GLM病灶及58个ILC病灶超声图像,对比分析两组患者的临床资料及超声声像图表现,包括病灶形态、纵横比、边界、周边晕环、内部导管扩张、液化区、钙化等。结果:两组病灶在发病年龄、红肿热痛等临床表现,以及超声显示的形态、内部导管扩张、液化区及钙化等方面差异均有统计学意义(P<0.05)。结论:GLM相较于ILC病灶内更易出现液化区、导管扩张、血流丰富等表现,综合分析超声与临床表现有助于提高对两者的鉴别诊断。

Objective: To summarize and compare the ultrasonographic features of granulomatous lobular mastitis(GLM) and infiltrating lobular carcinoma of the breast(ILC) for improving the differential diagnosis of them. Methods: The ultrasound images of 28 GLM lesions and 58 ILC lesions in Peking Union Medical College Hospital were retrospectively analyzed. The clinical data and ultrasound images of the lesions were compared and analyzed between the two groups, including morphology, aspect ratio,boundary, halo, ductal dilatation, fluid area, calcification. Results: There were significant differences between the two groups in clinical manifestations(age of onset, redness, swelling, heat and pain, etc.) and ultrasonographic features(morphology, internal catheter expansion, liquefaction area and calcification)(P<0.05). Conclusion: Compared with ILC, GLM is more likely to appear with liquid area, duct dilatation, rich blood flow. Comprehensive analysis of ultrasound imaging and clinical manifestations helps to improve the differential diagnosis of them.