基于数据挖掘探究近五年中医药治疗神经根型颈椎病用药规律

Exploring the Rules of Traditional Chinese Medicine for the Treatment of Cervical Spondylotic Radiculopathy based on Data Mining in the Past Five Year

目的:基于IBM SPSS Statistics 21.0及IBM SPSS Modeler 18.0数据处理软件,探究近五年中医治疗神经根型颈椎病的用药规律。方法:检索收集2016年1月1日至2021年1月1日中国知网、维普和万方数据库收录的文章,收集中药治疗神经根型颈椎病的文章102篇,通过精读文章,将联合其他药物组方、针灸、推拿等治疗方法及对照组组方与治疗组组方疗效无明显差异的文章剔除,筛选出其中的62篇,将文章中的治疗组组方提取出来,绘制成Excel表对相关药物进行初步整理,然后利用IBM SPSS Statistics21.0及IBM SPSS Modeler 18.0分析相关药物的使用频次、药物间的关联规则以及药物的核心组合。结果:对62首中药方中的102味中药进行频数统计,频数大于10的中药共计18味,其中前5味药分别是生甘草、葛根、白芍、桂枝、川芎,主要功效为祛风胜湿止痛、行气活血。对102味中药进行复杂网络图展示,共得出24对药物组合,对药物进行关联规则分析得到19个药对。对18味高频药物进行系统聚类共得到6个药物核心组合。结论:目前在临床上治疗神经根型颈椎病的中药以祛风除湿止痛药及行气活血药为主。

Objective Based on the data processing software of IBM spss statistics 21.0 and IBM spss modeler 18.0,to explore the rules of traditional Chinese medicine for the treatment of cervical spondylotic radiculopathy in clinics in recent years.Method By searching on January 1,2016 to January 1,2021 in China hownet,VIP and ten thousand articles published in the above,the collected about traditional Chinese medicine treatment of cervical spondylosis of nerve root type 102,through intensive reading the article,will unite other drug formula,acupuncture,massage and other treatments and the control group formula with no difference between the treatment group curative effect formula of articles,Sixty-two articles were screened out,and the treatment groups in the articles were extracted and drawn into an Excel table for preliminary sorting of related drugs.Then,IBM SPSS Statistics21.0 and IBM SPSS Modeler 18.0 were used to analyze the frequency of drug use,association rules between drugs and core drug combinations.Result The frequency statistics of 102 Chinese medicines in 62 Chinese medicine prescriptions were conducted.There were 18 Chinese medicines with a using frequency beyond 10,among which the top 5 medicines were sepatately sheng gan cao,ge gen,bai shao,guizhi and chuanxiong.The main effect is to expel wind,eliminate dampness and relieve pain,promotes qi to activate blood.A complex network diagram of 102 Chinese medicines was performed on,and a total of 24 medicines combinations were obtained,and then 19 chinese medicines pairs were obtained by association rules.A total of 6 medicines core combinations were obtained by systematic clustering from 18 high-frequency medicines.Conclusion At present,the traditional Chinese medicine for the clinical treatment of cervical spondylotic radiculopathy mainly consists of dispelling wind and dehumidifying painkillers and promoting qi and blood circulation drugs.