器官移植与寄生虫感染

Organ transplantation and parasitic infection

寄生虫感染兼具地方病与传染病的特点,其发病呈现一定地域性,并有传播属性。器官移植术后寄生虫感染的发生率较低,大多数分布于发展中国家与地区,多见于一些个案或病例报道。随着社会经济的发展以及器官移植病例数量的逐渐增加,移植受者在不同国家或地区之间的旅行增加,其暴露于寄生虫的机会亦增加,而免疫抑制状态又是寄生虫感染的危险因素,因此,器官移植受者寄生虫感染的风险不容忽视。本文就文献报道的器官移植术后寄生虫感染的流行病学特点、临床表现、诊断及治疗与预防进行分类综述,旨在为器官移植受者寄生虫感染的防治提供参考。

Parasitic infection is manifested with the characteristics of both endemic and infectious diseases,and the onset of parasitic infection is regional and infectious.The incidence of parasitic infection after organ transplantation is relatively low,primarily occurring in single case or case series in developing countries and regions.With the development of social economy and a gradual increasing number of organ transplantation,the risk of parasitic exposure is increased when the recipients travel among different countries or regions.In addition,immunosuppression is the risk factor of parasitic infection.Consequently,the risk of parasitic infection in organ transplant recipients cannot be ignored.In this article,epidemiological characteristics,clinical manifestations,diagnosis,treatment and prevention of parasitic infection after organ transplantation were classified and summarized according to literature review,aiming to provide reference for the prevention and treatment of parasitic infection in organ transplant recipients.