酒精相关精神病性障碍服药依从性调查及其影响因素分析

Medication compliance and influencing factors for alcohol-related psychotic disorders

目的 了解酒精相关精神病性障碍患者的服药依从性及其影响因素。方法 95例酒精相关精神病性障碍患者采用自制调查表收集患者临床资料,采用Morisky用药依从性量表评估服药情况,分析影响患者服药依从性相关因素。结果 单因素分析结果显示,文化程度、药物不良反应、经济水平、是否与监护人同住、服药知识情况与患者服药依从性有关(P<0.01或0.05)。多元回归分析显示,初中及以下学历、药物不良反应、经济水平差、未与监护人同住、不掌握服药知识是服药依从性危险因素(P<0.01或0.05)。结论 针对上述影响因素采取防治措施以提高酒精相关精神病性障碍患者的服药依从性。

Objective To study the medication compliance and influencing factors for alcohol-related psychotic disorders(ARPD). Methods Clinical data of 95 ARPD patients were collected by self-made questionnaire and their drug situation was evaluate by Morisky Medication Compliance Scale. The influencing factors for medication compliance were analyzed. Results The univariate analysis showed that education level, adverse effect, economic level, living with guardians, and medicine knowledge were related to medication compliance(P<0.01 or 0.05). The multivariate regression analysis revealed that middle school education or less, adverse effect, low economic level, not living with guardians, and less medicine knowledge were the risk factors for medication compliance(P<0.01 or 0.05). Conclusion The prevention and management measures targeting the above-mentioned risk factors can improve the medication compliance in ARPD patients.