应用腹腔镜结直肠癌根治术治疗老年结直肠癌的效果研究

Study on the effect of laparoscopic radical resection of colorectal cancer in the treatment of elderly colorectal cancer

目的探究腹腔镜结直肠癌根治术治疗老年结直肠癌的临床效果。方法选取江苏大学附属武进医院2016年12月至2021年3月收治的100例老年结直肠癌患者为研究对象,根据手术方式不同分为对照组(n=50)与研究组(n=50),对照组患者采用传统开腹手术,研究组患者应用腹腔镜结直肠癌根治术。对比两组患者手术实施情况及术后并发症发生情况,以及生活质量水平以及胃肠功能情况。结果两组患者术后生活质量评分较干预前都有明显提升,且研究组患者评分高于对照组(P<0.05);研究组患者术后并发症发生率为14.00%,明显低于对照组(P<0.05);在手术实施中,研究组患者手术时间、术中出血量、术后排气时间、术后住院时间、切除长度均明显优于对照组(P<0.05);研究组患者术后胃动素及胃泌素水平较术前有明显增高,且高于对照组(P<0.05)。结论对老年结直肠癌患者应用腹腔镜结直肠癌根治术临床效果更好,能有效降低老年患者的并发症发生率,且手术创伤较小,安全性更高,对提升老年结直肠癌患者的生活质量有积极意义。

Objective To explore the clinical effect of laparoscopic radical resection of colorectal cancer in the elderly.Method 100 elderly patients with colorectal cancer treated in Wujin Hospital Affiliated to Jiangsu University from December 2016 to March 2021 were selected as the research object.They were divided into control group(n=50)and study group(n=50)by different surgical methods.The patients in the control group were treated with traditional open surgery,and the patients in the study group were treated with laparoscopic radical resection of colorectal cancer.The operation implementation,postoperative complications,quality of life and gastrointestinal function were compared between the two groups.Result The scores of postoperative quality of life in the two groups were significantly higher than those before intervention,and the scores of patients in the study group were higher than those in the control group(P<0.05);the incidence of postoperative complications in the study group was 14.00%,which was significantly lower than that in the control group(P<0.05);during the operation,the operation time,intraoperative bleeding,postoperative exhaust time,postoperative hospital stay and resection length in the study group were significantly better than those in the control group(P<0.05);the levels of motilin and gastrin in the study group were significantly higher than those in the control group(P<0.05).Conclusion The clinical effect of laparoscopic radical resection of colorectal cancer in elderly patients is better.It can effectively reduce the incidence of complications in elderly patients,with less trauma and higher safety.It is of positive significance to improve the quality of life of elderly patients with colorectal cancer.