超声引导下不同路径神经阻滞在乳腺癌患者术中的麻醉镇痛效果及对认知功能的影响研究

Anesthesia and analgesia effect of ultrasound-guided nerve block with different routes in breast cancer patients and its influence on cognitive function

目的探讨超声引导下不同路径神经阻滞在乳腺癌患者术中的麻醉镇痛效果及对认知功能的影响。方法选取解放军陆军第七十三集团军医院于2020年1月至2021年1月所收治的100例乳腺癌患者,根据手术方式不同分为对照组(采用肋间神经阻滞+全身麻醉,50例)和观察组(采用胸壁神经阻滞+全身麻醉,50例)。比较两组患者的麻醉镇痛效果、认知功能及不良反应发生情况。结果和对照组相比,观察组患者在出恢复室、术后24h的疼痛评分明显更低,差异有显著性(P<0.05);术后,观察组患者认知功能水平明显提高,且高于对照组(P<0.05);观察组的不良反应发生率为8.00%,明显低于对照组的24.00%,差异有显著性(P<0.05)。结论针对乳腺癌患者,采用胸壁神经阻滞在镇痛方面获得了良好效果,降低了不良反应率。

Objective To investigate the effect of anesthesia and analgesia and the influence on cognitive function of different routes of nerve block guided by ultrasound in breast cancer patients.Method A total of 100 breast cancer patients admitted to the 73rd Group Military Hospital of the PLA Army from January 2020 to January 2021 were selected and divided into a control group(intercostal nerve block+general anesthesia,50 patients)and observation group(50 cases with chest wall nerve block+general anesthesia)by different surgical methods.The anesthesia and analgesia effect,cognitive function and occurrence of adverse reactions were compared between the two groups.Result Compared with the control group,the pain scores of patients in the observation group were significantly lower after leaving the recovery room and 24 hours after operation(P<0.05);after operation,the level of cognitive function in the observation group was significantly higher than that in the control group(P<0.05);the incidence of adverse reactions in the observation group was 8.00%,significantly lower than 24.00%in the control group(P<0.05).Conclusion For breast cancer patients,the use of chest wall nerve block has achieved good results in analgesia,greatly improved the patient's cognitive function,reduced the adverse reaction rate.