2019—2020年广州市本地新发现HIV/AIDS病例抗病毒治疗依从性分析

Analysis on compliance with antiviral therapy among HIV/AIDS cases newly identified in Guangzhou from 2019 to 2020

目的分析2019—2020年广州市本地新发现HIV/AIDS病例接受抗病毒治疗依从性情况。方法访问艾滋病防治信息系统,收集2019—2020年在广州本地发现和报告、现住址为广州市的HIV/AIDS病例信息,采用Logistic回归分析HIV/AIDS病例接受抗病毒治疗依从性的影响因素。结果2743例HIV/AIDS病例治疗率为91.5%(2509/2743),已婚有配偶[aOR(95%CI):1.65(1.10~2.46)],外地户籍[aOR(95%CI):1.38(1.02~1.88)],文化程度为初中[aOR(95%CI):1.75(1.15~2.64)]、高中或中专[aOR(95%CI):1.95(1.25~3.06)]、大专及以上[aOR(95%CI):3.16(1.90~5.25)],报告单位为艾滋病抗病毒治疗医院[aOR(95%CI):1.74(1.16~2.61)]、疾控中心[aOR(95%CI):2.81(1.76~4.48)]、社区卫生服务中心或镇卫生院[aOR(95%CI):1.76(1.07~2.90)],确诊时已进入艾滋病期[aOR(95%CI):1.68(1.23~2.30)]的病例接受抗病毒治疗比例高,≥50岁[aOR(95%CI):0.65(0.44~0.96)],通过异性性行为[aOR(95%CI):0.58(0.41~0.82)]或其他途径感染[aOR(95%CI):0.25(0.10~0.61)]的病例接受抗病毒治疗的比例低。结论2019—2020年广州市本地新发现HIV/AIDS病例抗病毒治疗依从性较好,应根据病例的特征有针对性地做好告知和治疗转介工作。

Objective To analyze the details of compliance with antiretroviral therapy among HIV/AIDS cases newly identified in Guangzhou from 2019 to 2020.Methods HIV/AIDS Prevention and Treatment System was accessed to,the information of HIV/AIDS cases diagnosed and living in Guangzhou currently from 2019 to 2020 were collected.The Logistic regression analysis was applied to identify factors of compliance with antiretroviral therapy.Results The treatment rate of 2743 HIV/AIDS cases was 91.5%(2509/2743),the married and conjugal patients[aOR(95%CI):1.65(1.10-2.46)],foreign household registration[aOR(95%CI):1.38(1.02-1.88)],patients graduated from junior high school[aOR(95%CI):1.75(1.15-2.64)],patients from senior high schools or technical secondary schools[aOR(95%CI):1.95(1.25-3.06)],patients from junior colleges and above[aOR(95%CI):3.16(1.90-5.25)],patients reported by antiretroviral therapy hospitals[aOR(95%CI):1.74(1.16-2.61)],patients from centers for disease control and prevention[aOR(95%CI):2.81(1.76-4.48)],patients from community healthcare centers or township hospitals[aOR(95%CI):1.76(1.07-2.90)],had progressed to AIDS by the time of HIV diagnosis[aOR(95%CI):1.68(1.23-2.30)]were more likely to receive antiretroviral therapy.The patients aged 50 years and over[aOR(95%CI):0.65(0.44-0.96)],infected through heterosexual behavior[aOR(95%CI):0.58(0.41-0.82)]or other routes[aOR(95%CI):0.25(0.10-0.61)]were less likely to receive antiretroviral therapies.Conclusion The newly identified HIV/AIDS cases in Guangzhou from 2019 to 2020 are found to have satisfactory compliance with antiviral theray,HIV-positive notification and antiretroviral therapy referral services should be tailored to the specific characteristics of individual patients.