可光降解聚羟基丁酸酯/聚己内酯基抗菌纤维膜的制备及其性能

Antibacterial fiber membrane with photodegradation function based on polyhydroxybutyrate/polycaprolactone

为开发一种具有高效抗菌性能和光降解功能的复合纤维膜,将Ag与ZnO复合,采用静电纺丝技术将不同质量分数的Ag-ZnO颗粒添加到聚己内酯(PCL)和聚羟基丁酸酯(PHB)复合材料中共混,制备了Ag-ZnO-PHB/PCL复合纤维膜。借助扫描电子显微镜、X射线衍射仪、热重分析和红外光谱等技术对复合纤维膜进行了表征,并评价其力学性能、光降解性能、抗菌性能及生物被膜作用。结果显示:该复合纤维膜对大肠杆菌和金黄色葡萄球菌的抑菌率在60 min时分别达到84.12%和97.99%,并在一定程度上对生物被膜起抑制作用;复合纤维膜在紫外光下照射12 min对亚甲基蓝溶液有显著的降解效果;复合纤维膜具有较好的力学性能与优良的生物相容性,有望应用于抗菌包装材料及生物医用领域。

In order to prepare a novel fiber membrane with high antibacterial performance and photodegradation function,Ag-ZnO composite particles with different mass fractions were added to polycaprolactone(PCL)and polyhydroxybutyrate(PHB)composite fiber membrane by electrospinning technology.The prepared Ag-ZnO-PHB/PCL fibrous membranes were characterized by scanning electron microscope,X-ray diffraction,thermogravimetric analysis,and fourier transform infrared spectroscopy.Mechanical properties,photocatalytic performance and antibacterial property were also investigated.The experimental data shows that the antibacterial rates of fibrous membranes against E.coli O157:H7 and S.aureus within 60 min reach 84.12%and 97.99%respectively.The fibrous membrane has inhibitory effect on biofilm to a certain extent.The degradation of methylene blue solution was significant when the fiber membrane was irradiated under ultraviolet light for 12 min.The fibrous membrane also has excellent mechanical properties and good biocompatibility,which demonstrates a great potential for application in the field of antibacterial packaging materials and medical dressings.