母乳中长链甘油三酯研究进展

Research Progresses of Medium-and Long-Chain Triacylglycerols in Human Milk

母乳中甘油三酯的结构对于婴幼儿的脂肪消化吸收具有重要影响。作者所在团队前期研究结果显示,母乳脂肪天然富含中长链甘油三酯(MLCT),是母乳中含量最丰富的一类甘油三酯,其质量约占总甘油三酯的30%,主要结构是一个中链脂肪酸和两个长链脂肪酸构成的单中链型甘油三酯(MLL)。母乳中几乎不含中链甘油三酯(MCT)。作者综述了母乳脂肪中MLCT的含量、组成、影响因素以及母乳与婴幼儿配方奶粉中甘油三酯的差异,总结了MLCT的消化特性,以及MLCT型母乳替代脂的研究进展,为新型配方奶粉脂肪的开发提供理论依据。

Triacylglycerols in human milk are important for infant lipid digestion and absorption.Previous research by our group has shown that human milk is naturally rich in medium-and longchain triacylglycerols(MLCT).MLCTs are the most abundant triacylglycerols in human milk,accounting for about 30%of the total triacylglycerols,and the main structure of MLCT is a single medium chain(MLL)type triglyceride with one medium-chain fatty acid and two long-chain fatty acids.There are few medium-chain triacylglycerols(MCT)in human milk.The content,composition and influencing factors of MLCT in human milk,and the differences between human milk and infant formulas are reviewed in this paper.The digestive and metabolic characteristics of MLCT are summarized,as well as the research progress of MLCT type human milk substitute fat.The research would provide theoretical basis for the development of infant formula.