重复经颅磁刺激早期干预对急性脑梗死患者功能障碍恢复作用的研究

Effect of early intervention of repetitive transcranial magnetic stimulation on the recovery of dysfunction in patients with acute cerebral infarction

目的 研究重复经颅磁刺激(rTMS)早期干预对急性脑梗死患者功能障碍恢复的作用。方法 收集2021年7月至2022年2月在我院神经内科治疗的急性脑梗死患者70例,按随机抽签方法分为观察组35例和对照组35例。观察组早期予常规治疗及重复经颅磁刺激治疗,对照组仅予常规治疗。观察两组患者临床疗效,以及治疗前后患者美国国立卫生研究院卒中量表(NIHSS)评分、日常生活能力量表(ADL)评分的变化。结果 观察组患者治疗后总有效率为94.28%,高于对照组的总有效率77.14%,差异具有统计学意义(P<0.05)。治疗后观察组的NIHSS评分为(6.68±6.01)分,低于对照组的NIHSS评分(7.79±4.46)分,两组对比差异具有统计学意义(P<0.05),且两组治疗前后NIHSS评分差值对比差异具有统计学意义(P<0.05)。治疗后,观察组患者的生活活动能力评分为(65.28±4.61)分,高于对照组的(53.00±3.27)分,两组对比差异具有统计学意义(P<0.05),且两组治疗前后ADL评分差值对比差异具有统计学意义(P<0.05)。结论 急性脑梗死患者早期进行重复经颅磁刺激干预可改善患者的症状,增强临床疗效,促进脑梗死患者功能尽早恢复,提高日常生活能力。

Objective To investigate the effect of repetitive transcranial magnetic stimulation(rTMS)on the recovery of motor dysfunction in patients with acute cerebral infarction.Methods 70 patients with acute cerebral infarction treated in neurology department of our hospital from July 2021 to February 2022 were randomly divided into observation group and control group,with 35 cases in each group.The experimental group received early conventional treatment and repeated transcranial magnetic stimulation,while the control group received conventional treatment.Treatment effect,national Institutes of Health Stroke Scale(NIHSS)score and Daily Living Scale(ADL)score before and after treatment in 2 groups were observed.Results The total effective rate of observation group was 94.28%after treatment,which was higher than that of control group(77.14%),and the difference between the two groups was statistically significant(P<0.05).After treatment,the NIHSS score of the observation group was 6.68±6.01,lower than that of the control group(7.79±4.46),the difference between the two groups was statistically significant(P<0.05),and the difference between the two groups before and after treatment was statistically significant(P<0.05).After treatment,the living activity score of the observation group was 65.28±4.61,higher than that of the control group(53.00±3.27),the difference between the two groups was statistically significant(P<0.05),and the difference of ADL score between the two groups before and after treatment was statistically significant(P<0.05).Conclusion Early repetitive transcranial magnetic stimulation intervention in patients with acute cerebral infarction can improve the symptoms of patients,enhance clinical efficacy,promote the early recovery of functional disorders in patients with cerebral infarction,improve the ability of daily life.