性别及相关因素影响人体衰弱的研究进展

Research progress of gender and related factors affect human frailty

衰弱是一种以多系统功能累积性下降为主要特征的病理性状态,患者会面临日常活动受限、生活自理能力降低与并发症风险增加的问题。男性与女性在身体构造、生活习惯以及工作类型等方面存在诸多不同,使其发生衰弱的概率也存在差异。进一步明确导致该差异的相关因素,将帮助医务工作者更好地了解衰弱的发病机制,为不同性别的衰弱患者制定更具针对性的防治计划。本文从生物学、行为学及社会学三个层面阐述性别及相关因素对人体衰弱发生发展产生的影响,寻找针对性防治男性与女性衰弱的措施。

Frailty is a pathological condition characterized by a cumulative decline in multi-system function,in which patients face limited daily activities,reduced ability to take care of themselves,and an increased risk of complications.Men and women differ in body structure,lifestyle,and type of work,leading to differences in frailty between the sexes.Further clarification of the factors contributing to this difference will help medical workers better understand frailty's pathogenesis and develop a more targeted cure schedule for frail patients of different genders.This paper reviews the effects of gender and related factors on the occurrence and development of frailty in the human body from three aspects of biology,behavior,and sociology,looking for r targeted measures to prevent frailty in men and women.