乳腺癌生存者经济毒性现状与影响因素分析

Status and influencing factors of cancer-related financial toxicity of breast cancer survivors

目的:调查乳腺癌生存者的经济毒性现状,并分析其影响因素。方法:采用方便抽样方法,应用一般资料调查表、慢性病治疗经济毒性功能评估综合评分量表、心理弹性量表、领悟社会支持量表和M.D.Anderson症状评估量表,于2021年6月-10月对上海市徐汇区3家社区卫生服务中心和1个患者团体组织的乳腺癌生存者进行横断面调查。结果:共纳入312名乳腺癌生存者,其经济毒性得分为(22.70±8.39)分。多元线性回归结果显示,乳腺癌生存者的年龄、受教育水平、化疗、独居、个人月总收入、家庭可支配存款、心理弹性、症状困扰程度是经济毒性的影响因素,可解释总变异的28.5%。结论:经济毒性在乳腺癌生存者中普遍存在,影响其生活质量。除人口学因素外,心理弹性、症状困扰程度与癌症相关经济毒性存在关系,这为今后开发针对经济毒性的干预策略提供了新的视角。

Objective:To investigate the current situation of cancer-related financial toxicity of breast cancer survivors,and analyze the influencing factors.Methods:Using the convenient sampling method,breast cancer survivors were investigated with the demographic and disease information questionnaire,COST-FACIT,CD-RISC 10,PSSS and MDASI in three community health centers and a cancer survivors group in Xuhui district,Shanghai.Results:The average score of COST-FACIT of 312 breast cancer patients was 22.70±8.39.The multivariate linear regression analysis showed that age,education,chemotherapy,living alone,personal monthly income,household savings,psychological resilience and symptoms were independent influencing factors of financial toxicity,which accounted 28.5%of the total variation.Conclusion:Financial toxicity is generally existent in breast cancer survivors,affecting their quality of life.In addition to demographic factors,breast cancer survivors'psychological resilience and symptoms are related to the cancer-related financial toxicity.The study provides a new perspective for the development of intervention for financial toxicity in the future.