超声造影定量参数预测卵巢癌合并淋巴结转移的研究

Prediction of Lymph Node Metastasis in Ovarian Cancer by Quantitative Parameters of Contrast-enhanced Ultrasound

目的研究超声造影(CEUS)定量参数预测卵巢癌合并淋巴结转移的价值。方法回顾性分析63例卵巢癌患者临床资料,纳入卵巢癌组;收集同时期我院确诊的62例卵巢癌合并淋巴结转移患者临床资料,纳入淋巴结转移组。记录并对比两组患者的CEUS定量参数,包括通过时间、显影时间、达峰时间以及峰值强度,并分析通过时间、显影时间、达峰时间以及峰值强度预测卵巢癌合并淋巴结转移的价值。结果淋巴结转移组的通过时间、显影时间、达峰时间、峰值强度较卵巢癌组低,差异有统计学意义(P<0.05);绘制受试者工作特征曲线(ROC曲线),得到CEUS定量参数通过时间、显影时间、达峰时间、峰值强度预测卵巢癌合并淋巴结转移的曲线下面积(AUC)分别为0.817、0.863、0.807、0.844。结论CEUS定量参数可预测卵巢癌合并淋巴结转移,为卵巢癌的临床诊治提供依据。

Objective To study the value of quantitative parameters of contrast-enhanced ultrasound(CEUS)in predicting lymph node metastasis of ovarian cancer.Methods The clinical data of 63 patients with ovarian cancer diagnosed were retrospectively analyzed and included in the ovarian cancer group;the clinical data of 62 patients with ovarian cancer complicated with lymph node metastasis diagnosed in our hospital during the same period were collected and included in the lymph node metastasis group.The quantitative parameters of CEUS,including transit time,development time,peak time and peak intensity,were recorded and compared between the two groups,and the value of transit time,development time,peak time and peak intensity in predicting ovarian cancer with lymph node metastasis was analyzed.Results The transit time,development time,peak time and peak intensity of lymph node metastasis group were lower than those of ovarian cancer group,the difference was statistically significant(P<0.05);the receiver operating characteristic curve(ROC curve)was drawn,and the area under the curve(AUC)of CEUS quantitative parameters such as transit time,development time,peak time and peak intensity to predict ovarian cancer with lymph node metastasis was0.817、0.863、0.807、0.844.Conclusion CEUS parameters can predict lymph node metastasis of ovarian cancer and provide a basis for clinical diagnosis and treatment of ovarian cancer.