五味子及其内生菌代谢产物的研究进展

Research Progress on Metabolites of Schisandra chinensis and Its Endophytes

五味子及其内生菌的代谢产物多样,在现有基础上对其进行深入研究至关重要。通过介绍五味子及其内生菌代谢产物的研究进展,综述国内外相关文献,总结归纳五味子内生菌类别以及代谢产物的种类和药理作用。五味子的内生菌主要有两大类,即内生真菌和内生细菌;五味子及其内生菌的活性代谢产物主要有木脂素类、挥发油类、多糖类、三萜化合物和有机酸等,代谢产物的药理作用主要集中在抗菌、抗肿瘤、抗氧化、肝病治疗和改善神经系统等方面。为治疗人类多种疾病提供可能,具有广阔应用前景。

The metabolites of Schisandra chinensis and its endophytes are diverse.It is very important to study Schisandra chinensis and its endophytes on the basis of the existing research.By introducing the research progress on metabolites of Schisandra chinensis and its endophytes,relevant domestic and international literatures were reviewed to summarize the types of endophytes of Schisandra chinensis,and the types and pharmacological effects of their metabolites.There are two main types of endophytes in Schisandra chinensis endophytic fungi and endophytic bacteria.In recent years,the research on the products of Schisandra chinensis and its endophytes has been focused on lignans,volatile oils,polysaccharides,triterpenoids,organic acids and so on.The pharmacological effects of these metabolites are mainly focused on antibacterial,anti-tumor,anti-oxidation,liver disease treatment and improvement of the nervous system.It will provide more possibilities for the treatment of various human diseases and has broad application prospects.