亲水型TiO2纳米阵列的制备及其抗菌性能的研究

Preparation and Study on Its Antibacterial Properties of Hydrophilic TiO_(2) Nanoarray

近年来研究发现,自然界材料表面结构的特异性,可通过制备相似仿生材料实现。鉴于抗菌材料的广泛需求和应用,仿生抗菌材料成为研究热点之一。由于其化学性质稳定、廉价易得及生物相容性良好,TiO_(2)材料可被用于仿生抗菌材料的研究,而制备具有仿生结构的可控TiO_(2)纳米阵列材料具有很大的研究意义。利用简易的水热合成法,通过调控反应时间在掺杂氟的SnO_(2)导电玻璃(FTO)上成功制备TiO_(2)纳米阵列材料,进行了物化性能和抗菌性能测试。材料物化分析表明:随着反应时间的增加,TiO_(2)纳米阵列沿(002)晶相排布更密集,且表面水接触角从85.97°逐渐变化为19.11°。材料的表面抗菌实验结果表明,TiO_(2)纳米阵列材料对革兰氏阴性菌和阳性菌均表现出了良好的抗菌效果,这将为制备表面亲水性的抗菌复合材料提供备选材料。

In recent years, it has been found that the specificity from the surface structure of natural materials can be achieved by preparing similar biomimetic materials.In view of the wide range of needs and applications of antibacterial materials, biomimetic antibacterial materials have become one of the research hotspots.Due to its stable chemical properties, low cost and good biocompatibility, TiO_(2)material can be used in the research of biomimetic antibacterial materials.There is a great research significance on the preparation of controllable biomimetic TiO_(2)nanoarray materials.Using a simple hydrothermal synthesis method, the TiO_(2)nanoarray material was successfully prepared on the fluorine-doped SnO;conductive glass(FTO) substrate by adjusting the reaction time, and tested the physicochemical properties and antibacterial properties.It shows that with the increase of the reaction time, the TiO_(2)nanoarrays are arranged more densely along the crystal phase(002),and the surface water contact angle gradually changes from 85.97° to 19.11°.It also shows the good antibacterial effect on both Gram-negative bacteria and positive bacteria to be an alternative material for the preparation of antibacterial composite materials with hydrophilic surfaces.