经支气管冷冻肺活检在间质性肺炎患者诊断及评估中的临床价值

Clinical Value of Transbronchial Cryobiopsy in the Diagnosis and Evaluation of Patients with Interstitial Pneumonia

目的:探究经支气管冷冻肺活检(TBCB)在间质性肺炎患者诊断及评估中的临床价值。方法:选取2019年6月-2020年12月因间质性肺炎诊断不明需行肺活检的73例患者为研究对象,全麻状态下先后对患者行TBCB和常规经支气管肺活检(TBLB),比较TBCB和TBLB对间质性肺炎的诊断效能。结果:两组均获得活检标本224个,TBCB组标本大小明显大于TBLB组,手术操作时间长于TBLB组(P<0.05);两组均无严重的气胸,TBCB组出血发生率为47.32%,明显高于TBLB组(P<0.05);TBCB组病理活检阳性率为79.45%,明显高于TBLB组(P<0.05)。结论:TBCB在活检标本大小及间质性肺炎分型诊断效能明显优于常规TBLB,且安全性良好。

Objective:To explore the clinical value of transbronchial cryobiopsy(TBCB)in the diagnosis and evaluation of patients with interstitial pneumonia.Methods:A total of 73 patients undergoing lung biopsy due to non-determined diagnosis of interstitial pneumonia from June 2019 to December 2020 were enrolled as the research objects.Under general anesthesia,all patients underwent TBCB and routine transbronchial lung biopsy(TBLB)in turn.The diagnostic efficiency of TBCB and TBLB for interstitial pneumonia was compared.Results:There were 224 biopsy specimens in each group.The size of specimens in TBCB group was significantly larger than that in TBLB group,and operation time was longer than that in TBLB group(P<0.05).There was no serious pneumothorax in both groups.The incidence of bleeding in TBCB group was 47.32%,significantly higher than that in TBLB group(P<0.05),and positive rate of pathological biopsy in TBCB group was 79.45%,significantly higher than that in TBLB group(P<0.05).Conclusion:The diagnostic efficiency of TBCB is significantly better than that of routine TBLB for size of biopsy specimens and interstitial pneumonia classifications,with better safety.