冠状动脉粥样硬化斑块愈合的研究进展

Research progress of coronary atherosclerotic plaque healing

动脉粥样硬化斑块破裂后的愈合过程对临床结果意义重大,良好的斑块愈合可以阻止血栓的进一步发展,避免急性心血管事件的发生,但反复的斑块愈合也被认为可加重斑块负荷,引起血管慢性狭窄。随着腔内影像技术的发展,对斑块愈合的研究愈加深入,许多针对斑块愈合的治疗方法也在实施或研究中。

The atherosclerotic plaque healing process after plaque rupture is of great significance to clinical results.Plaque healing can prevent the further development of thrombus and avoid the occurrence of acute cardiovascular events.However,repeated plaque healing can also cause chronic vascular stenosis.Plaque healing can be divided into three stages:thrombolysis,granulation tissue formation and vascular re-endothelialization,which are also affected by various local and systemic factors.With the development of new imaging techniques,the research on plaque healing is getting deeper,and many treatments for plaque healing are being used or studied.