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原发性干燥综合征发病机制的研究进展 被引量:8

Research progress of pathogenesis of primary Sjogren’s syndrome
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摘要 原发性干燥综合征(pSS)是一种慢性自身免疫性疾病,其发病机制尚未明确,也无较好的治疗方法。随着分子生物学技术日趋成熟,pSS研究已逐步向分子水平深入,本文就目前国内外pSS发病机制研究进行综述,以期为明确其发病机制及探究其治疗方法提供参考。 Primary Sjogren’s syndrome(pSS)is a chronic autoimmune disease without clear pathogenesis and better treatment. With development of molecular biology technology,research of pSS has gradually developed into molecular level. In this paper,current research on pathogenesis of pSS at home and abroad is reviewed,to provide references for clarifying pathogenesis of pSS and exploring its treatment methods.
作者 刘茂华 聂敏海 陈中林 刘旭倩(指导) LIU Maohua;NIE Minhai;CHEN Zhonglin;LIU Xuqian(Department of Periodontics&Oral Mucosal Diseases,the Affiliated Stomatology Hospital of Southwest Medical University,Luzhou 646000,China)
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2022年第8期1017-1020,共4页 Chinese Journal of Immunology
基金 四川省泸州市科知局科技计划项目(2019-JYJ-54) 四川省干部保健普及应用项目(川干研2022-2101) 四川省科技厅中央引导地方科技发展专项项目(2021ZYD0083)。
关键词 原发性干燥综合征 发病机制 靶向治疗 表观遗传修饰 代谢异常 Primary Sjogren’s syndrome Pathogenesis Targeted therapy Epigenetic modification Metabolic disorder
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