期刊文献+

单剂肿瘤坏死因子α拮抗剂联合糖皮质激素治疗Stevens-Johnson综合征2例

Two cases of Stevens-Johnson syndrome controlled by single dose of tumor necrosis factor-α antagonist combined with glucocorticoids
原文传递
导出
摘要 例1女,71岁,2020年9月8日因全身红疹伴口唇黏膜破溃7 d于东部战区总医院就诊。2020年8月因右膝关节积液伴疼痛曾于外院静脉滴注地塞米松、口服头孢类药物等。9月2日因消化道出血外院予头孢尼西钠、奥美拉唑及输血等治疗,期间躯干、四肢新发红疹,口唇黏膜破溃,伴瘙痒、高热,予地塞米松、马来酸氯苯那敏、异丙嗪等治疗后热退,但皮损未见明显好转,遂至我院急诊科静脉滴注甲泼尼龙40 mg,以Stevens-Johnson综合征(Stevens-Johnson syndrome,SJS)转入皮肤科。
作者 陈其英 陈军 曾梅华 惠云 谢小鸳 桑红 孔庆涛 Chen Qiying;Chen Jun;Zeng Meihua;Hui Yun;Xie Xiaoyuan;Sang Hong;Kong Qingtao(Department of Dermatology,General Hospital of Eastern Theater Command,The First School of Clinical Medicine,Southern Medical University,Nanjing 210002,China;The Fourth Affiliated Hospital of Nanjing Medical University,Nanjing 210031,China;Department of Dermatology,General Hospital of Eastern Theater Command,Nanjing 210002,China)
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2022年第7期612-613,共2页 Chinese Journal of Dermatology
基金 江苏省医学创新团队培养项目(CXTDA2017038)。
  • 相关文献

参考文献4

二级参考文献21

  • 1Paquet P, Nikkels A, Arrese JE, et al. Macrophages and tumor necrosis factor alpha in toxic epidermal necrolysis. Arch Dermatol, 1994, 130(5): 605-608.
  • 2Correia O, Delgado L, Barbosa IL, et al. Increased interleukin 10, tumor necrosis factor alpha, and interleukin 6 levels in blister fluid of toxic epidermal necrolysis. J Am Acad Dermatol, 2002, 47 ( 1 ): 58-62.
  • 3Nassif A, Moslehi H, Le Gouvello S, et al. Evaluation of the potential role of cytokines in toxic epideruml neerolysis. J Invest Dermatol, 2004, 123(5): 850-855.
  • 4Wolf R, Matz H, Marcos B, et al. Drug rash with eosinophilia and systemic symptoms vs toxic epidermal neerolysis: the dilemma of classification. Clin Dermatol, 2005, 23(3 ): 311-314.
  • 5Fischer M, Fiedler E, Marsch WC, et al. Antitumour necrosis factor-alpha antibodies (infliximab) in the treatment of a patient with toxic epidermal necrolysis. Br J Dermatol, 2002, 146 (4): 707-709.
  • 6Hunger RE, Hunziker T, Buettiker U, et al. Rapid resolution of toxic epidermal necrolysis with anti-TNF-alpha treatment. J Allergy Clin lmmunol, 2005, 116(4): 923-924.
  • 7A1-Sbouli S, Abouchala N, Bogusz MJ, et al. Toxic epidermalnecrolysis associated with high intake of sildenafil and its response to infliximab. Acta Derm Venereol, 2005. 85 (6): 534- 535.
  • 8Gubinelli E, Canzona F, Tonanzi T, et al. Toxic epidermalnecrolysis successfully treated with etanercept. J Dermatol, 2009, 36(3): 150-153.
  • 9陈金波,王宝玺,王宏伟,曾跃平,徐浩翔.Stevens—Johnson综合征及中毒性表皮坏死松解症61例回顾性分析[J].中华皮肤科杂志,2008,41(8):542-545. 被引量:19
  • 10杨永生,徐金华,李锋,朱小华.静脉注射丙种球蛋白和糖皮质激素治疗重症大疱性药疹65例[J].中华皮肤科杂志,2009,42(5):330-332. 被引量:36

共引文献131

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部