多排螺旋CT结合碘克沙醇对图像质量及肾功能的影响

Effects of Multi-slice Spiral CT Combined with Iodixanol on Image Quality and Renal Function

本研究探讨多排螺旋CT结合等渗对比剂碘克沙醇对图像质量及肾功能的影响。选取行多排螺旋CT检查冠心病患者110例,根据对比剂不同分为观察组(n=60)和对照组(n=50),两组均给予多排螺旋CT检查,其中观察组给予等渗对比剂碘克沙醇,对照组给予碘海醇,分析两组图像质量以及肾功能情况。观察组和对照组图像质量主观评价结果比较差异无统计学意义(P>0.05);观察组和对照组升主动脉根部、左主干、右冠状动脉起始部CT值、噪声(SD)、信噪比(SNR)和对比噪声比(CNR)比较差异无统计学意义(P>0.05);观察组造影后血肌酐(Scr)和尿素氮(BUN)明显低于对照组(P<0.05);观察组不良反应发生率为1.67%,明显低于对照组(P<0.05)。多排螺旋CT结合等渗对比剂碘克沙醇有较高应用价值,图像质量佳,对患者肾功能无明显影响。

This paper discussed the effect of multi-slice spiral CT combined with isotonic contrast agent iodixanol on image quality and renal function was discussed.110 coronary heart disease patients underwent multi-slice spiral CT were selected,and divided them into observation group(n=60)and control group(n=50)according to different contrast media,both groups were given multi-slice spiral CT examination.The observation group was given isosmotic contrast agent iodixanol,and the control group was given iohexol,the image quality and renal function of the two groups were analyzed.There was no significant difference in the subjective evaluation results of image quality between the observation group and the control group(P>0.05).There were no significant differences in CT values,noise value(SD),signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of ascending aortic root,left main artery and right coronary artery between observation group and control group(P>0.05).The serum creatinine(Scr)and blood urea nitrogen(BUN)after angiography in observation group were significantly lower than those in control group(P<0.05).The incidence of adverse reactions in observation group was 1.67%,which was significantly lower than that in control group(P<0.05).Multi slice spiral CT combined with isotonic contrast agent iodixanol has high application value,good image quality and no significant effect on renal function.