高原病患者血压水平流行病学特征及其与糖代谢相关性分析

Prevention suggestion based on the correlation between epidemiological characteristics of blood pressure level and glucose metabolism in patients with altitude sickness

目的探讨高原病患者血压水平的流行病学分布特征,糖代谢异常等因素对高原并患者血压异常的影响,借以提出预防方案。方法从青海省心脑血管病专科医院高血压高原病科2017年1月至2021年6月间确诊的高原病患者358例中选取符合研究纳入标准的259例进行分析(剔除既往已诊断高血压者99例,最终259例受试对象),收集血压、血糖水平和其他潜在影响因素等信息,分析关联并讨论合理的预防策略。使用SPSS 19.0统计。结果新诊断高血压患者的收缩压平均(154.36±12.58)mmHg,舒张压平均(93.69±9.54)mmHg,脉压差为(61.25±10.28)mmHg,(与对照组比较t/P值:16.505/<0.001、10.122/<0.001和13.644/<0.001);患者同时伴有血糖、血脂异常;基于流行特征拟合预防高原病患者血压水平异常的回归方程,可见年龄更大的体力劳动从业者出现高原病并见高血压的风险会更高,且血脂异常,血糖增高以及吸烟习惯均与高原病患者并见高血压风险增加存在潜在关联,回归方程:y=-2.611-0.070x_(1)+0.130x_(2)+0.874x_(3)+0.849x_(4)+0.309x_(5)+0.341x_(6)+0.895x_(7)-0.064x_(8)。结论加强高原病患者慢性病相关健康知识宣传教育,增强其对高血糖等高危因素认识,有效控制血糖血脂等均对于预防并发高血压具有积极作用。

Objective To explore the epidemiological distribution characteristics of blood pressure in patients with altitude sickness,and the influence of abnormal glucose metabolism and other factors on abnormal blood pressure in patients with altitude sickness,so as to propose preventive plans.Methods From the 358 patients with altitude sickness diagnosed in our hospital from January 2017 to June 2021,259 patients who met the inclusion criteria of this study were selected for analysis(99 patients with previously diagnosed hypertension were excluded,and the final 259 patients)The study selected 259 subjects,collected information on blood pressure,blood glucose levels,and other potential influencing factors,analyzed associations,and discussed reasonable prevention strategies.Statistics using SPSS19.0.Results The mean systolic blood pressure of newly diagnosed hypertensive patients was(154.36±12.58)mmHg,the diastolic blood pressure was(93.69±9.54)mmHg,and the pulse pressure difference was(61.25±10.28)mmHg,(compared with the control group t/P value:16.505/<0.001,10.122/<0.001 and 13.644/<0.001);the patients were accompanied by dysglycemia and dyslipidemia at the same time;the regression equation for preventing abnormal blood pressure levels in patients with altitude sickness was fitted based on epidemiological characteristics,and it can be seen that older manual labor practitioners have high altitude The risk of high blood pressure is higher in patients with high altitude sickness,and dyslipidemia,elevated blood sugar and smoking habits are potentially associated with the increased risk of high altitude sickness and high blood pressure.Regression equation:y=-2.611-0.070x_(1)+0.130x_(2)+0.874x_(3)+0.849x_(4)+0.309x_(5)+0.341x_(6)+0.895x_(7)-0.064x_(8).Conclusion Strengthening the publicity and education of health knowledge related to chronic diseases in patients with altitude sickness,enhancing their awareness of high-risk factors such as hyperglycemia,and effective control of blood sugar and blood lipids have positive effects on preventing complicated hypertension.