术前焦虑与围术期不良事件相关性的研究进展

Research advances of correlation between preoperative anxiety and perioperative adverse events

术前焦虑是围术期患者最常见的临床问题之一。许多研究表明,术前焦虑与围术期不良事件的发生密切相关,如失眠、术后疼痛、术后恶心呕吐、术后谵妄等。术前焦虑与围术期不良事件发生机制的关联目前尚未完全清楚,可能涉及多个系统功能的调节紊乱。针对术前焦虑进行合理的干预或治疗,或将有助于减少围术期不良事件的发生。本文选择失眠、术后疼痛、术后恶心呕吐及术后谵妄等较为典型围术期不良事件,从术前焦虑与围术期不良事件的关系、发生机制及干预策略等角度予以综述。

Preoperative anxiety is one of the most common clinical problems in perioperative patients.Numerous studies have confirmed that preoperative anxiety is closely related to the occurrence of adverse events,such as insomnia,postoperative pain,postoperative nausea and vomiting and postoperative delirium.However,its mechanism is not completely clear,which may involve multiple systems dysfunctions.Appropriate intervention or treatment for preoperative anxiety will contribute to reduce the incidence of perioperative adverse events.In this paper,typical perioperative adverse events,such as insomnia,postoperative pain,postoperative nausea and vomiting,and postoperative delirium,were selected to review the relationship between preoperative anxiety and perioperative adverse events,their mechanisms and intervention strategies.