摘要
发展了一种高效的烯烃、二芳基二硒醚和烷基胺的分子间胺硒化策略,在铜盐和高价碘试剂条件下,以较高产率获得一系列的β-氨基硒化物.初步的实验结果表明,反应涉及活性硒自由基中间体,并提出了自由基反应机理.
An efficient protocol for the intermolecular amidoselenation of alkenes with diphenyl diselenides and alkyl amines has been developed,affording a series ofβ-amido-selenides in high yields under copper salt and(diacetoxyiodo)benzene(PIDA)conditions.The preliminary experimental results supported the involvement of active selenide radical species,and a radical pathway was therefore proposed for the reaction.
作者
殷一樊
李晨
孙凯
刘颖杰
王薪
Yin Yifan;Li Chen;Sun Kai;Liu Yingjie;Wang Xin(Department of Chemistry&Biochemistry,New Mexico State University,New Mexico,88011 USA;School of Pharmacy,Harbin University of Commerce,Harbin 150076;College of Chemistry and Chemical Engineering,Yantai University,Yantai,Shandong 264005)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2022年第5期1431-1437,共7页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21801007)资助项目.
