加味黄芪桂枝五物汤治疗糖尿病周围神经病变的可行性及临床分析

Feasibility and Clinical Analysis of Modified Huangqi Guizhi Wuwu Decoction in the Treatment of Diabetic Peripheral Neuropathy

目的探讨加味黄芪桂枝五物汤治疗糖尿病周围神经病变的可行性及临床分析。方法选取该院2020年10月—2021年10月收治糖尿病周围神经病变患者80例,以随机数字法将其分为对照组(n=40,行常规治疗)与观察组(n=40例,行加味黄芪桂枝五物汤治疗),对比两组患者临床治疗效果。结果观察组临床总有效率97.90%高于对照组80.00%,差异有统计学意义(P<0.05)。治疗前,两组FPG、2 hPG相近,差异无统计学意义(P>0.05);治疗后,观察组FPG、2 hPG低于对照组,差异有统计学意义(P<0.05)。治疗后,两组胫神经运动传导速度、腓总神经运动传导速度及腓肠神经感觉传导速度较治疗前均显著提升,且观察组优于对照组,差异有统计学意义(P<0.05)。结论加味黄芪桂枝五物汤治疗糖尿病周围神经病变临床疗效较高且可提升患者神经运动传导速度,改善患者肢体疼痛及麻木等症状,具有可行性。

Objective To investigate the feasibility and clinical analysis of modified Huangqi Guizhi Wuwu Decoction in the treatment of diabetic peripheral neuropathy.Methods A total of 80 diabetic patients admitted to the hospital from October 2020 to October 2021 were selected and divided into control group(n=40,conventional treatment)and observation group(n=40 patients,treated with modified Huangqi Guizhi Wuwu Decoction),compared the two groups of clinical treatment effect.Results The total clinical effective rate of observation group was 97.90%higher than that of control group 80.00%,and the difference was statistically significant(P<0.05).Before treatment,the difference in FPG and 2 hPG between the two groups was not statistically significant(P>0.05);after treatment,the FPG and 2 hPG of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the motor conduction velocity of tibial nerve,the motor conduction velocity of common peroneal nerve and the sensory conduction velocity of sural nerve in the two groups were significantly improved compared with those before treatment,and the observation group was better than the control group,the difference was statistically significant(P<0.05).Conclusion The modified Huangqi Guizhi Wuwu Decoction has a high clinical efficacy in the treatment of diabetes peripheral neuropathy,and can improve the neuromotor conduction velocity of patients,improve the symptoms of limb pain and numbness,which is feasible.