摘要
从棕榈花中分离鉴定了2个新的莽草酸衍生物以及4个生源相关的莽草酸衍生物.综合运用多种波谱技术以及化学反应确定了所得化合物的结构.所有分离得到的化合物均具有α-葡萄糖苷酶抑制活性,其中trachshikimic B(2),3-feruloylquinic acid(5)和chlorogenic acid(6)的活性强于阳性对照阿卡波糖.
Two new shikimic acid-derived trachshikimics A and B,together with four known biogenetically related shikimic acid derivatives,were isolated from the flower of Trachycarpus fortunei(Hook.)H.Wendl.Their structures were elucidated using comprehensive spectroscopic methods and chemical reaction.All isolated compounds showedα-glucosidase inhibitory activities,while Trachshikimic B(2),3-feruloylquinic acid(5)and chlorogenic acid(6)were more active than the positive control acarbose.
作者
林芳霞
王治鸿
代德财
周学明
吴禄勇
Lin Fangxia;Wang Zhihong;Dai Decai;Zhou Xueming;Wu Luyong(Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education,College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158;Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province,Hainan Vocational University of Science and Technology,Haikou 571126;Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province,College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2022年第4期1248-1251,共4页
Chinese Journal of Organic Chemistry
基金
海南省自然科学基金(Nos.220QN252,218QN234)资助项目。
关键词
棕榈
莽草酸衍生物
α-葡萄糖苷酶抑制活性
Trachycarpus fortunei
shikimic acid derivative
α-glucosidase inhibitory activity
