银杏蜜环口服溶液治疗高血压合并冠心病心绞痛的临床疗效研究

Clinical Effect of Ginkgo Mihuan Oral Solution in the Treatment of Hypertension Complicated with Coronary Heart Disease and Angina Pectoris

目的:研究冠状动脉粥样硬化心绞痛患者采用银杏蜜环口服液搭配硝酸酯类常规药物治疗的临床应用价值。方法:选择2021年1月—8月黑龙江中医药大学附属第一医院收治的97例冠心病心绞痛患者作为研究对象,按照随机数表法分为研究组与对照组。对照组50人进行常规硝酸酯类治疗,研究组47人进行常规硝酸酯类药物治疗外加服银杏蜜环口服液。对比两组患者治疗效果。结果:治疗后研究组患者收缩压舒张压恢复情况优于对照组,差异有统计学意义(t=3.262、2.04,P<0.05),心电图恢复总有效率高于对照组,差异有统计学意义(χ^(2)=5.127,P<0.05),心绞痛发病次数,持续时间,硝酸甘油用量少于对照组,差异有统计学意义(t=7.623、7.433、6.891,P<0.05),改善症状时间明显短于对照组,住院时间明显短于对照组,差异有统计学意义(t=7.575、11.27,P<0.05)。治疗前两组患者生活质量评分,差异无统计学意义(t=0.574,P>0.05),治疗后研究组患者生活质量评分明显高于对照组,差异有统计学意义(t=29.51,P<0.05)。结论:冠状动脉粥样硬化心绞痛采用银杏蜜环口服液搭配硝酸酯类治疗效果比单一使用硝酸酯类基础治疗效果提升显著,突出降低血压,改善心肌功能,减少心绞痛发作次数,缩短心绞痛持续时间,促进相关症状缓解,提高治疗效率,加快住院痊愈时间,提高治疗后生活质量,为患者愈后生活带来保障。

Objective:To study the clinical application value of ginkgo biloba oral liquid combined with conventional nitrates in the treatment of patients with coronary atherosclerotic angina pectoris.Methods:A total of 97 patients with coronary heart disease and angina pectoris admitted to the hospital from January to August 2021 were selected as the research subjects,and divided into the study group and the control group according to the random number table method.50 cases in the control group were treated with conventional nitrates,and 47 cases in the research group were treated with conventional nitrates and Ginkgo Mihuan Oral Liquid.The treatment effects of the two groups were compared.Results:After treatment,the recovery of systolic and diastolic blood pressure in the study group was better than that in the control group,and the difference was statistically significant(t=3.262,2.040,P<0.05).The total effective rate of ECG recovery was higher than that of the control group,and the difference was statistically significant(χ^(2)=5.127,P<0.05).The incidence of angina pectoris,duration,and nitroglycerin dosage were less than those in the control group,and the difference was statistically significant(t=7.623,7.433,6.891,P<0.05).The symptom improvement time and hospital stay were significantly shorter than those in the control group,and the difference was statistically significant(t=7.575,11.270,P<0.05).There was no statistically significant difference in the quality of life scores between the two groups before treatment(t=0.574,P>0.05).After treatment,the quality of life score of the patients in the study group was significantly higher than that in the control group,and the difference was statistically significant(t=29.51,P<0.05).Conclusion:The effect of Ginkgo Mihuan oral liquid combined with nitrates in the treatment of coronary atherosclerotic angina pectoris was significantly improved than that of the basic treatment with nitrates alone.It focuses on lowering blood pressure,improving myocardial function,reducing the number of angina pectoris attacks,shortening the duration of angina pectoris,promoting the relief of related symptoms,improving the treatment efficiency,speeding up the recovery time in hospital,improving the quality of life after treatment,and guaranteeing the patients’life after recovery.