改良小切口甲状腺切除术和传统甲状腺切除术治疗甲状腺结节的效果分析

Analysis of the Effect of Modified Small Incision Thyroidectomy and Traditional Thyroidectomy in the Treatment of Thyroid Nodules

目的:对比改良小切口甲状腺切除术和传统甲状腺切除术治疗甲状腺结节的临床疗效。方法:选取2018年10月—2020年9月广州市荔湾区中医医院住院治疗的94例甲状腺结节患者作为研究对象,按单盲随机抽样法分为参照组和实验组,每组各47例。参照组采用传统甲状腺切除术治疗,实验组采用改良小切口甲状腺切除术治疗。对比两组患者手术指标、甲状腺功能指标、血清炎性因子指标及并发症发生率情况。结果:实验组手术时间、切口长度、住院时间均短于参照组,差异有统计学意义(t=13.939、26.556、10.995,P<0.05);实验组术中出血量低于参照组,差异有统计学意义(t=16.225,P<0.05);实验组治疗后血清游离甲状腺素(FT3)、游离三碘甲状腺原氨酸(FT4)、肿瘤坏死因子-a(TNF-a)、白细胞介素-6(IL-6)、C反应蛋白(CRP)因子均低于参照组,血清促甲状腺激素(TSH)高于参照组,差异有统计学意义(P<0.05);实验组并发症发生率低于参照组,差异有统计学意义(χ2=6.114,P<0.05)。结论:改良小切口甲状腺切除术治疗甲状腺结节对患者甲状腺功能影响较小,且手术时间较短,术后炎症反应较轻,并发症发生率较低,值得借鉴。

Objective:To compare the clinical efficacy of modified small incision thyroidectomy and traditional thyroidectomy in the treatment of thyroid nodules.Methods:94 patients with thyroid nodules in the hospital from October 2018 to September2020 were selected and divided into control group and experimental group by single blind random sampling method,with 47 cases in each group.The control group was treated with traditional thyroidectomy,and the experimental group was treated with modified small incision thyroidectomy.The operation indexes,thyroid function indexes,serum inflammatory factors and complications of the two groups were compared.Results:The operation time,incision length and hospitalization time in the experimental group were shorter than those in the control group,the difference was statistically significant difference(t=13.939,26.556,10.995,P<0.05).The intraoperative blood loss in the experimental group was lower than that in the control group,the difference was statistically significant difference(t=16.225,P<0.05).The serum FT3,FT4,TNF-a,IL-6 and CRP factors in the experimental group after treatment were lower than those in the control group,and the serum TSH in the experimental group was higher than that in the control group,the difference was statistically significant difference(P<0.05).The incidence of complications in the experimental group was lower than that in the reference group,the difference was statistically significant difference(χ2=6.114,P<0.05).Conclusion:Modified small incision thyroidectomy for thyroid nodules has less influence on thyroid function,shorter operation time,less postoperative inflammatory reaction and lower incidence of complications,which is worthy of reference.