近五年泉州地区复发性急性胰腺炎临床特征分析

Clinical characteristics of recurrent acute pancreatitis in Quanzhou in recent five years

目的探讨泉州地区复发性急性胰腺炎(RAP)的发病情况和临床特点,为今后RAP的诊治和预防提供帮助。方法收集2016年1月—2020年12月RAP患者纳入复发组,并经性别年龄匹配初发性急性胰腺炎患者纳入初发组,采用统计学方法进行回顾性分析。结果(1)近五年我院住院AP患者中近1/3为RAP,纳入复发组158例,其中男性患者120例,25~50岁患者占75.95%,复发次数2~18次。(2)复发组主要病因依次为高脂血症性(68.99%)、胆源性(15.82%)、酒精性(10.76%)、特发性(4.43%),初发组主要病因依次为高脂血症性(56.33%)、胆源性(21.52%)、特发性(11.39%)、酒精性(10.76%),复发组高脂血症性胰腺炎的比例明显高于初发组(P<0.05)。(3)2组病情比较发现复发组轻症胰腺炎比例较高,其次为中度重症、重症(54.43%、36.71%、8.86%),而初发组中度重症胰腺炎比例较高,其次为轻症、重症(48.73%、39.24%、12.03%)(P<0.05)。初发组胸腹腔积液的发生率明显高于复发组(P<0.05)。(4)复发组的平均住院天数和平均住院费用低于初发组(P<0.05)。结论RAP在青中年男性中高发;高脂血症是RAP的主要病因,相比初发组RAP患者病情较轻,平均主要天数和平均住院费用较低。对青中年男性高脂血症性胰腺炎患者,需注意饮食、健康宣教和血脂管理,以减少RAP的发生。

Objective To investigate the incidence and clinical characteristics of recurrent acute pancreatitis(RAP),which can provide useful information for the treatment and prevention of RAP.Methods The RAP patients from January 2016 to December 2020 were divided into the recurrent group,and the patients with only one attack of pancreatitis after gender and age matching were divided into the primary group.The clinical data in the two groups were collected and analyzed using a statistical method.Results(1)Nearly 1/3 of the AP patients in our hospital in the past five years were RAP,and 158 cases were divided into the recurrent group.Among them,120 were male,and patients aged 25~50 accounted for 75.95%.The number of relapses was 2~18.(2)The main causes of the recurrent group was hyperlipidemia(68.99%),biliary diseases(15.82%),alcohol(10.76%),idiopathic(4.43%);however,the main causes of the primary group was hyperlipidemia(56.33%),biliary diseases(21.52%),idiopathic(11.39%),alcohol(10.76%).The proportion of hyperlipidemic acute pancreatitis in the recurrent group was significantly higher than that in the primary group(P<0.05).(3)Comparing the conditions of the two groups,it was found that the recurrent group had a higher proportion of mild acute pancreatitis,followed by moderately severe and severe(54.43%,36.71%,8.86%),while the primary group had a higher proportion of moderately severe pancreatitis,followed by They were mild and severe(48.73%,39.24%,12.03%)(P<0.05).The incidence of pleural effusion and ascites in the primary group was significantly higher than that in the recurrent group(P<0.05).(4)The length of hospital stay and the hospitalization expense was lower than those of the primary group(P<0.05).Conclusion RAP occurs frequently among young and middle-aged men;hyperlipidemia is the main cause of RAP.Compared with the primary group,the condition of RAP patients are milder,with shorter length of hospital stay and lower hospitalization expense.Pay attention to propaganda and education of diet as well as management of blood lipid in young and middle-aged male HLAP patients,which can reduce RAP.