基于前馈控制模式的三联干预措施应用于肺癌化疗患者的效果观察

Efficacy of feedforward control-based triple intervention in patients with lung cancer on chemotherapy

目的探讨基于前馈控制模式的三联干预措施对肺癌化疗患者的干预效果。方法选取2019年12月至2020年12月间上海中医药大学附属曙光医院收治的行化疗治疗的110例肺癌患者进行研究,采用随机数表法分成观察组和对照组,每组55例。对照组患者采用常规干预措施,观察组患者采用基于前馈控制模式的三联干预措施。比较两组患者干预前及干预3个月后的肺功能指标[用力肺活量(FVC)、1秒用力呼气容积(FEV_(1))、1秒用力呼气容积与用力肺活量比值(FEV_(1)/FVC)]、生活质量、并发症发生率及干预效果。结果干预后,两组患者FVC、FEV_(1)、FEV_(1)/FVC均较干预前明显升高,且观察组高于对照组,差异有统计学意义(P<0.05)。干预后,两组患者生活质量量表躯体功能、生理功能、情绪功能和社会功能评分均较干预前明显升高,且观察组明显高于对照组,差异均有统计学意义(均P<0.05)。观察组患者并发症发生率为14.5%,明显低于对照组的32.7%,差异有统计学意义(P<0.05)。观察组患者干预总有效率为96.4%,高于对照组的76.4%,差异有统计学意义(P<0.05)。结论基于前馈控制模式的三联干预措施对肺癌化疗患者的干预效果好,能降低并发症发生率,值得临床推广及应用。

Objective To investigate the efficacy of feedforward control-based triple intervention in patients with lung cancer on chemotherapy. Methods From December 2019 to December 2020, 110 patients undergoing chemotherapy for lung cancer were selected at Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Using the random number table method, they were divided into an observation group and a control group with 55 patients in each group. The observation group was given feedforward control-based triple intervention besides routine intervention and the control group was given routine intervention. Lung function indexes including forced vital capacity(FVC), forced expiratory volume in 1 second(FEV_(1)), ratio of forced expiratory volume in 1 second to forced vital capacity(FEV_(1)/FVC), quality of life score, incidence of complications, and the efficacy of intervention were compared and analyzed in the two groups. Results After the intervention, FVC, FEV_(1), FEV_(1)/FVC were significantly higher than those before the intervention in the two groups, and these index levels were significantly higher in the observation group than in the control group(all P<0.05). After the intervention, quality of life scale scores including physical, physiological, emotional and social function were significantly higher than those before the intervention in the two groups, and these index levels were was significantly higher in the observation group than in the control group(all P<0.05). The overall efficacy of intervention was 96.4% in the observation group which was significantly higher than 76.4% of the control group(P<0.05). Conclusion Triple intervention based on feedforward control shows good treatment efficacy and it reduces the incidence of complications in patients with lung cancer on chemotherapy. It is worthy of clinical promotion and application.